{"id":"W2042357419","doi":"10.1073/pnas.1407567111","title":"Evolved tooth gain in sticklebacks is associated with a <i>cis</i> -regulatory allele of <i>Bmp6</i>","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"dental development and anomalies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Dental and Craniofacial Research; National Institute of General Medical Sciences; National Human Genome Research Institute; National Science Foundation; National Institutes of Health; March of Dimes Foundation; Pew Charitable Trusts; Howard Hughes Medical Institute","keywords":"Biology; Stickleback; Quantitative trait locus; Allele; Population; Genetic architecture; Genetics; Locus (genetics); Evolutionary biology; Gasterosteus; Gene; Fishery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007415086,0.00007230366,0.0001218621,0.00005984147,0.00004496602,0.000007259559,0.0003776247,0.00007162683,0.000005270733],"category_scores_gemma":[0.0002174052,0.00004846585,0.00003922337,0.0002849225,0.0004941223,0.00001758962,0.00009363121,0.00005119821,2.544778e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009622642,"about_ca_system_score_gemma":0.00003399248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002592862,"about_ca_topic_score_gemma":6.900288e-7,"domain_scores_codex":[0.9989962,0.000005983995,0.0002109721,0.0001660709,0.0005135516,0.0001072128],"domain_scores_gemma":[0.9995368,0.00002196662,0.0002671482,0.000007815319,0.0001488372,0.0000174145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003542523,0.00006135124,0.06972937,0.00002904129,0.00002205686,3.147598e-9,0.0001136718,0.0000345196,0.9255985,0.002361911,0.001863474,0.0001506796],"study_design_scores_gemma":[0.0003245047,0.0001020253,0.1605627,0.00008561542,0.000005526813,0.000001217867,0.00009793489,0.0001471256,0.8356574,0.002524906,0.000412947,0.00007808284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926533,0.00006764843,0.000001751376,0.0003438448,0.000006235733,0.00007718772,0.000008191801,0.000002093929,0.006839817],"genre_scores_gemma":[0.9987099,0.00001384058,0.00042332,0.0003330825,0.00001896955,0.000003943751,9.55377e-7,0.000003262863,0.0004927114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09083334,"threshold_uncertainty_score":0.197638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01329555286108364,"score_gpt":0.2451403572306642,"score_spread":0.2318448043695806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}