{"id":"W2042357419","doi":"10.1073/pnas.1407567111","title":"Evolved tooth gain in sticklebacks is associated with a <i>cis</i> -regulatory allele of <i>Bmp6</i>","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"dental development and anomalies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Dental and Craniofacial Research; National Institute of General Medical Sciences; National Human Genome Research Institute; National Science Foundation; National Institutes of Health; March of Dimes Foundation; Pew Charitable Trusts; Howard Hughes Medical Institute","keywords":"Biology; Stickleback; Quantitative trait locus; Allele; Population; Genetic architecture; Genetics; Locus (genetics); Evolutionary biology; Gasterosteus; Gene; Fishery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009649884,0.0002311569,0.0001472849,0.0003790536,0.0002042442,0.0001962754,0.0001800108,0.0002327503,0.001054015],"category_scores_gemma":[0.0001124801,0.0001640007,0.0001935063,0.000125193,0.0002460944,0.00008628142,0.0003403669,0.0004999616,0.0001589925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002361311,"about_ca_system_score_gemma":0.0001243452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001152332,"about_ca_topic_score_gemma":0.002632254,"domain_scores_codex":[0.9999081,0.000007570433,0.000008267481,0.00003598807,0.00002580354,0.00001436805],"domain_scores_gemma":[0.9998197,0.00002221023,0.00008169742,0.0000173386,0.00001257923,0.00004647881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00006106343,0.00000899338,0.007485623,0.00001113162,0.000007458278,0.00008251897,0.0000233736,0.00003579379,0.9907549,0.0000348678,0.00001287703,0.001481387],"study_design_scores_gemma":[0.00002109559,0.0003614691,0.85948,0.000008314327,0.00004632091,0.001562125,0.00009586461,0.001007646,0.1365607,0.0001485388,0.0006863675,0.0000215455],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990981,0.00006028386,0.0004799595,0.00001316515,0.000002940062,0.000003366734,0.00009410052,0.00001839981,0.0002296951],"genre_scores_gemma":[0.9978716,0.00006555106,0.0007623236,0.00004404867,0.000005897514,0.000009647045,0.0002747744,0.00001579247,0.0009503666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001152332,"threshold_uncertainty_score":0.003526032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01329555286108364,"score_gpt":0.2451403572306642,"score_spread":0.2318448043695806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}