{"id":"W2042372127","doi":"10.1159/000086898","title":"The association of skewed X chromosome inactivation with aneuploidy in humans","year":2005,"lang":"en","type":"review","venue":"Cytogenetic and Genome Research","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia; BC Research (Canada); University of British Columbia","funders":"","keywords":"Aneuploidy; Biology; Trisomy; Skewed X-inactivation; Genetics; X-inactivation; X chromosome; DNA methylation; Chromosome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004060123,0.000492544,0.0009834901,0.001872849,0.0002024369,0.0004775131,0.0004592735,0.0006418903,0.002067786],"category_scores_gemma":[0.0008176028,0.0001971908,0.0002206289,0.002573139,0.0003378926,0.0005753197,0.0003651562,0.000498852,0.001255666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003583188,"about_ca_system_score_gemma":0.0006871432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001558398,"about_ca_topic_score_gemma":0.002022692,"domain_scores_codex":[0.9998179,0.00003179932,0.00003046432,0.00004274734,0.00006492383,0.00001204366],"domain_scores_gemma":[0.9997167,0.0001188862,0.00006435932,0.000007742753,0.00007549431,0.00001690597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007868974,0.00002013121,0.0013868,0.01133179,0.0001182236,0.001315375,0.00009207663,0.000229443,0.002544151,0.0009937505,0.01299889,0.9688905],"study_design_scores_gemma":[0.00002661938,0.0001185931,0.01216616,0.003985378,0.0002778945,0.02120891,0.0001959406,0.00006784764,0.001350758,0.001825653,0.9587453,0.00003101637],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003601202,0.9982989,0.0001213326,0.0001591472,0.00007322512,0.000002699306,0.00001396655,0.000005889976,0.0009646024],"genre_scores_gemma":[0.00180532,0.997317,0.0001863887,0.0001108533,0.00006232668,0.000003387995,0.00002430023,8.831162e-7,0.000489577],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002067786,"threshold_uncertainty_score":0.006917417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1100416686638978,"score_gpt":0.4119454254936636,"score_spread":0.3019037568297658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}