{"id":"W2042411369","doi":"10.1038/nature01912","title":"Phagosomes are competent organelles for antigen cross-presentation","year":2003,"lang":"en","type":"article","venue":"Nature","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":688,"is_retracted":false,"has_abstract":false,"ca_institutions":"Caprion (Canada); Université de Montréal","funders":"Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale","keywords":"Phagosome; Cross-presentation; Antigen presentation; MHC class I; Endoplasmic reticulum; Antigen processing; Antigen; Major histocompatibility complex; Cell biology; Biology; Cytoplasm; CD8; Phagocytosis; Microbiology; T cell; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002538702,0.0002429902,0.0003082481,0.0002613752,0.0003448315,0.001165683,0.0002432426,0.001105227,0.001404118],"category_scores_gemma":[0.000218885,0.0001814624,0.0001342536,0.0001703278,0.0004750861,0.000936165,0.0004503085,0.0006965655,0.001554568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000503842,"about_ca_system_score_gemma":0.0003120352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001931944,"about_ca_topic_score_gemma":0.0003147364,"domain_scores_codex":[0.9998716,0.00002668777,0.000007522272,0.00001989664,0.00004590825,0.00002843392],"domain_scores_gemma":[0.99988,0.00002716461,0.00002309612,0.00001613852,0.00002854504,0.00002511324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000498752,0.00004874896,0.001078826,0.0005306333,0.00001945147,0.0006658876,0.00011553,0.0002433941,0.894958,0.03729075,0.007324775,0.05722534],"study_design_scores_gemma":[0.00004951296,0.0002630056,0.007345589,0.0001012265,0.00005200064,0.004111425,0.000232431,0.001292941,0.6954542,0.02162953,0.2694435,0.00002454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.437853,0.4031375,0.07708425,0.01001193,0.003722619,0.0001576527,0.001257611,0.001207869,0.06556749],"genre_scores_gemma":[0.9034073,0.05518674,0.0103829,0.001029653,0.0004644918,0.0000470839,0.0006395598,0.00006245437,0.02877972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001404118,"threshold_uncertainty_score":0.004697204,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190900217588949,"score_gpt":0.2973467393500601,"score_spread":0.2854377371741706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}