{"id":"W2042487540","doi":"10.1016/j.bbamem.2007.08.034","title":"NMR structural studies of the antibiotic lipopeptide daptomycin in DHPC micelles","year":2007,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":78,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Daptomycin; Lipopeptide; Micelle; Antibiotics; Microbiology; Chemistry; Stereochemistry; Biology; Bacteria; Vancomycin; Organic chemistry; Staphylococcus aureus; Aqueous solution","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002130366,0.0004638081,0.0005241453,0.000296875,0.0001065686,0.0002432222,0.0004063383,0.0003425845,0.0005719125],"category_scores_gemma":[0.0001860596,0.0001912879,0.0001231999,0.0003927314,0.0002345136,0.0004352427,0.0002284692,0.0004596721,0.0004573833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004879866,"about_ca_system_score_gemma":0.0002300965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000617393,"about_ca_topic_score_gemma":0.0005340432,"domain_scores_codex":[0.9999475,0.000006761102,0.00000396615,0.00001586598,0.0000178762,0.000008045595],"domain_scores_gemma":[0.9999262,0.00002231526,0.00001749193,0.000005182516,0.00002247737,0.000006197326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000266798,0.00005974441,0.0001695137,0.004505408,0.00003041828,0.0003544169,0.00006809869,0.001192246,0.7064874,0.001265272,0.002417705,0.2831831],"study_design_scores_gemma":[0.0000481186,0.0003927264,0.002552752,0.0003258727,0.0001429209,0.002099884,0.0001006328,0.001706741,0.7573233,0.0007793579,0.2344894,0.00003830358],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05948656,0.9256434,0.006918897,0.0006271278,0.0003570284,0.00004007846,0.0001544859,0.0001047059,0.006667763],"genre_scores_gemma":[0.1076423,0.8774362,0.006380878,0.0004051995,0.000259208,0.000035504,0.0003729731,0.00002625889,0.007441581],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.000617393,"threshold_uncertainty_score":0.003540576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06302630960435746,"score_gpt":0.3472712734448304,"score_spread":0.284244963840473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}