{"id":"W2042520547","doi":"10.1038/nsmb.2838","title":"It takes two to tangle: Prp24 and spliceosome assembly","year":2014,"lang":"en","type":"letter","venue":"Nature Structural & Molecular Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Tangle; Spliceosome; Computational biology; Cell biology; Biology; Chemistry; Genetics; RNA splicing; RNA; Gene; Mathematics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002094894,0.0005817824,0.0008100217,0.0004355363,0.002594691,0.002823449,0.001116909,0.0209764,0.006182419],"category_scores_gemma":[0.009701392,0.0005792147,0.0008076602,0.0002279609,0.002799801,0.002967932,0.001766478,0.01680457,0.002940438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002390134,"about_ca_system_score_gemma":0.001079024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008470567,"about_ca_topic_score_gemma":0.001445124,"domain_scores_codex":[0.9989875,0.0002187241,0.00008105877,0.0001617232,0.0003572635,0.0001936567],"domain_scores_gemma":[0.9971982,0.001374106,0.0002451169,0.0002900165,0.0003017449,0.0005908299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008698559,0.0001243468,0.001504248,0.0001171806,0.00008839345,0.006478077,0.0001441397,0.0004939665,0.003897814,0.02582386,0.9006144,0.05984366],"study_design_scores_gemma":[0.0006852943,0.000359411,0.002218804,0.0001668452,0.0001169681,0.006312676,0.0003537239,0.003191557,0.008270276,0.1529588,0.8252307,0.0001349332],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.005413753,0.005454035,0.001489357,0.9368397,0.04279609,0.00002121088,0.00005161482,0.0001693966,0.007764818],"genre_scores_gemma":[0.1029971,0.006373493,0.002065924,0.7107448,0.1253285,0.0001571625,0.0001078837,0.00009160218,0.05213366],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0209764,"threshold_uncertainty_score":0.02068228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006377685084817151,"score_gpt":0.3216582987626341,"score_spread":0.315280613677817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}