{"id":"W2042589623","doi":"10.1159/000134380","title":"Interaction of the HMG-CoA Reductase Inhibitor Lovastatin and Nitric Oxide in Cardiomyocyte Cell Death","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Lovastatin; Reductase; Viability assay; Programmed cell death; HMG-CoA reductase; Nitric oxide; Apoptosis; Statin; Cerivastatin; Sodium nitroprusside; Chemistry; Pharmacology; Biochemistry; Biology; Endocrinology; Enzyme; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002794893,0.0002577824,0.0005243529,0.000136596,0.0001922528,0.0003684525,0.0002131274,0.000398282,0.0005808264],"category_scores_gemma":[0.0001629017,0.0001194461,0.0003132423,0.00009333398,0.0002021954,0.0002204913,0.0001726343,0.0002966243,0.0002794272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003171234,"about_ca_system_score_gemma":0.0003098903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004193416,"about_ca_topic_score_gemma":0.001237343,"domain_scores_codex":[0.9996593,0.0001025585,0.00003813221,0.00005429524,0.00008497341,0.00006069695],"domain_scores_gemma":[0.9998699,0.00003646378,0.00003279095,0.0000112539,0.00002343508,0.00002611684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008426586,0.00009166857,0.0009511119,0.0001246994,0.00003520028,0.0001341163,0.0000192656,0.00007759374,0.995017,0.00007237417,0.00003582036,0.002598513],"study_design_scores_gemma":[0.00005596866,0.001810475,0.00898763,0.00001542232,0.00006891166,0.0005053954,0.00006142601,0.0008163216,0.9849194,0.00004980296,0.002703377,0.000005859429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766397,0.01898057,0.002500761,0.0002526563,0.0001068671,0.00004557615,0.0001089639,0.00003112598,0.001333637],"genre_scores_gemma":[0.9923437,0.004278408,0.001699598,0.0001081156,0.00004119024,0.00002897866,0.000117947,0.000006055113,0.001376054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005808264,"threshold_uncertainty_score":0.002300918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01433850801960096,"score_gpt":0.2739749250456835,"score_spread":0.2596364170260825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}