{"id":"W2042590551","doi":"10.1126/science.1134301","title":"Genomic Insights into the Immune System of the Sea Urchin","year":2006,"lang":"en","type":"review","venue":"Science","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":443,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Biology; Deuterostome; Sea urchin; Innate immune system; Genome; Gene; Pattern recognition receptor; Immune system; Acquired immune system; Evolutionary biology; Gene family; Leucine-rich repeat; Genetics; Receptor; Vertebrate; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002901528,0.0006098127,0.0007545387,0.001159938,0.0002147362,0.0007903656,0.0006220013,0.0007560498,0.002311507],"category_scores_gemma":[0.0002852315,0.0002096859,0.0001719356,0.001124789,0.0005621259,0.000868738,0.0004936447,0.0008566926,0.00162209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005968639,"about_ca_system_score_gemma":0.0007615025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001458223,"about_ca_topic_score_gemma":0.001838496,"domain_scores_codex":[0.9999226,0.00001087722,0.00001107463,0.00002071632,0.00002495904,0.000009827442],"domain_scores_gemma":[0.9998817,0.00002999573,0.00001632643,0.0000069078,0.00004546921,0.00001959525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008277564,0.00002566269,0.0006543676,0.003972271,0.0000338061,0.0006161312,0.00009193562,0.0003512663,0.01301262,0.004153339,0.01254019,0.9644656],"study_design_scores_gemma":[0.00001283597,0.00008586076,0.004520516,0.0009807437,0.00006324042,0.002411472,0.000112843,0.0001057052,0.002026915,0.003422723,0.9862433,0.00001377216],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009279567,0.996166,0.0002810264,0.0004726368,0.0001873825,0.000002746036,0.0000210078,0.0000127616,0.001928543],"genre_scores_gemma":[0.004479289,0.9927465,0.0003878478,0.0003482801,0.0002525251,0.000004908757,0.00006121687,0.000001751886,0.001717654],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002311507,"threshold_uncertainty_score":0.007732749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01611367855095289,"score_gpt":0.2581402903346542,"score_spread":0.2420266117837014,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}