{"id":"W2042650545","doi":"10.1371/journal.pone.0012443","title":"Disruption of the Lipid-Transporting LdMT-LdRos3 Complex in Leishmania donovani Affects Membrane Lipid Asymmetry but Not Host Cell Invasion","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Instituto de Salud Carlos III; Deutsche Forschungsgemeinschaft; McMaster University","keywords":"Infectivity; Phosphatidylserine; Leishmania donovani; Phosphatidylethanolamine; Biology; Cell biology; Lipid bilayer; Lipid microdomain; Phosphatidylcholine; Cell membrane; Phospholipid; Biochemistry; Membrane; Virology; Visceral leishmaniasis; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001450883,0.0002898271,0.0002422968,0.0001486527,0.0001976104,0.0003199076,0.0002528975,0.0004041456,0.0008417769],"category_scores_gemma":[0.0001569924,0.0001782358,0.0001996924,0.0001157168,0.000436119,0.0001849905,0.0002419621,0.0004182732,0.0002555567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004198075,"about_ca_system_score_gemma":0.0001912691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008926892,"about_ca_topic_score_gemma":0.001006514,"domain_scores_codex":[0.9998761,0.0000301769,0.00001711882,0.00001819649,0.00003016217,0.00002813161],"domain_scores_gemma":[0.9998908,0.00002074685,0.00003896421,0.00001353762,0.000007699791,0.00002814407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001385463,0.00001729403,0.0001452293,0.00002015664,0.000005461945,0.00006460315,0.00001011055,0.00003399762,0.9992459,0.00009017993,0.00001328201,0.0002152163],"study_design_scores_gemma":[0.00003345564,0.0001515126,0.003030162,0.000004147525,0.00001882746,0.0004188029,0.00003376797,0.000873486,0.9943303,0.00005171629,0.001049626,0.000004197811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987168,0.0002319801,0.000651223,0.00006147419,0.00000905981,0.000007423116,0.00009032131,0.00002100585,0.0002105958],"genre_scores_gemma":[0.9984907,0.0001120569,0.0005940966,0.00002682142,0.000002559377,0.0000089886,0.0001522269,0.00001499486,0.0005975312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008926892,"threshold_uncertainty_score":0.003045976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05736987670781429,"score_gpt":0.2774687100146496,"score_spread":0.2200988333068353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}