{"id":"W2042659287","doi":"10.1016/j.jbspin.2013.05.007","title":"Characterization of opticin digestion by proteases involved in osteoarthritis development","year":2013,"lang":"en","type":"article","venue":"Joint Bone Spine","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Children's Hospital; Université de Montréal","funders":"Instituto de Salud Carlos III; Manchester Biomedical Research Centre; Eli Lilly and Company","keywords":"Osteoarthritis; Proteases; Medicine; Digestion (alchemy); Pathology; Biochemistry; Biology; Chemistry; Chromatography; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002740794,0.0003802788,0.0002380707,0.000391557,0.0002283605,0.000354348,0.0001581228,0.0002798551,0.001134268],"category_scores_gemma":[0.0003194091,0.0001799842,0.0005368093,0.0002169781,0.0003096891,0.000380006,0.0001643863,0.0004093668,0.0003079297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003151009,"about_ca_system_score_gemma":0.0002743725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001290226,"about_ca_topic_score_gemma":0.001334203,"domain_scores_codex":[0.9998401,0.00002392518,0.0000199585,0.00002838683,0.00003048947,0.00005707716],"domain_scores_gemma":[0.9997961,0.00004545218,0.00005790786,0.00001802785,0.00003747686,0.00004510105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007090637,0.0000265526,0.00265334,0.00005180785,0.00002144152,0.0002394534,0.00003916765,0.00004092082,0.9941329,0.0001006632,0.0000253301,0.001959445],"study_design_scores_gemma":[0.00003900787,0.0004790797,0.08800907,0.000021343,0.0001046606,0.001604911,0.0002059003,0.001133688,0.9045773,0.0001293878,0.003683529,0.00001203957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924533,0.002754451,0.003023342,0.00007513967,0.0000190144,0.00003953798,0.0003448352,0.000009268248,0.001281193],"genre_scores_gemma":[0.9886686,0.001434162,0.005169772,0.00008835109,0.00002008046,0.00004108135,0.001418246,0.00001416002,0.003145581],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001290226,"threshold_uncertainty_score":0.003794551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01314993007552494,"score_gpt":0.2181176913667692,"score_spread":0.2049677612912443,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}