{"id":"W2042688172","doi":"10.1016/j.cell.2005.08.031","title":"Exploration of the Function and Organization of the Yeast Early Secretory Pathway through an Epistatic Miniarray Profile","year":2005,"lang":"en","type":"article","venue":"Cell","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":893,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Biology; Epistasis; Computational biology; Function (biology); Gene; Yeast; Cluster analysis; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003675811,0.0004723235,0.0002649454,0.0006547653,0.0002741301,0.000605207,0.0003596685,0.0003188061,0.001673747],"category_scores_gemma":[0.0003906383,0.00031483,0.000339549,0.0003358558,0.0002993691,0.0003330726,0.000476087,0.0007994149,0.0005635139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005194152,"about_ca_system_score_gemma":0.0003490306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001040423,"about_ca_topic_score_gemma":0.002125175,"domain_scores_codex":[0.999769,0.0000304567,0.00001661724,0.00006115405,0.00008377099,0.00003907083],"domain_scores_gemma":[0.9995314,0.0001468966,0.0001018051,0.0000632486,0.00006722449,0.0000895563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002866026,0.00000288208,0.00009431804,0.000004103996,0.000001246842,0.00001249534,0.000004445255,0.00002089138,0.9992201,0.00008574245,0.000007285556,0.0005178721],"study_design_scores_gemma":[0.00001088118,0.0001166378,0.01179139,0.000003120798,0.00003050344,0.0005417163,0.00003710621,0.002272915,0.9834114,0.0001686773,0.001603195,0.00001248534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9444892,0.0007374543,0.05107649,0.0002980062,0.00003027296,0.00005314671,0.0009107527,0.0003467181,0.002057905],"genre_scores_gemma":[0.9612701,0.0006771268,0.03028537,0.0002263454,0.00002027495,0.00006970927,0.001212926,0.0002691581,0.005969011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001673747,"threshold_uncertainty_score":0.00559926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01389407049796213,"score_gpt":0.2248546472854351,"score_spread":0.210960576787473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}