{"id":"W2042816955","doi":"10.1016/s0041-1345(00)02325-3","title":"ISATX247: a novel calcineurin inhibitor","year":2001,"lang":"en","type":"article","venue":"Transplantation Proceedings","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Calcineurin; Medicine; Pharmacology; Internal medicine; Transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008696674,0.000126696,0.0000766797,0.00003658749,0.00005985207,0.00002704412,0.000121112,0.00008944531,0.00003746178],"category_scores_gemma":[0.00002803627,0.0001305908,0.00005582277,0.0001159621,0.00003847166,0.000008107425,0.00001092063,0.0000610191,0.00002625988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008272919,"about_ca_system_score_gemma":0.0000306293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006810124,"about_ca_topic_score_gemma":0.000002661092,"domain_scores_codex":[0.9992164,0.000003263072,0.0001618955,0.0002913888,0.0001422559,0.0001847685],"domain_scores_gemma":[0.9996848,0.000004880543,0.00004753299,0.00007570779,0.00009411294,0.00009304011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002846912,0.00007024526,0.009098619,0.00005835586,0.00001466297,0.000006913364,0.0002034119,0.00001439915,0.9885115,0.0002882868,0.001247684,0.0002012394],"study_design_scores_gemma":[0.001453291,0.000154335,0.005760854,0.00003868038,0.00004689529,0.0001895343,0.00007382419,0.00004912745,0.9796041,0.00007472255,0.01230515,0.0002494351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932356,0.00006553529,0.002986251,0.0001750654,0.0001050224,0.0001489906,0.00003038059,0.00005241539,0.00320072],"genre_scores_gemma":[0.997533,0.00009601999,0.0007935924,0.0004702623,0.0003128421,0.00003414322,0.0001096152,0.0000247679,0.000625792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01105747,"threshold_uncertainty_score":0.5325337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01545672778845745,"score_gpt":0.2507375182724478,"score_spread":0.2352807904839903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}