{"id":"W2042822986","doi":"10.1021/ml500322h","title":"Aptamer-Facilitated Cryoprotection of Viruses","year":2014,"lang":"en","type":"article","venue":"ACS Medicinal Chemistry Letters","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aptamer; Vesicular stomatitis virus; Virology; DNA; Viral load; Viral replication; Virus; Biology; Chemistry; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004024901,0.0001638273,0.0001778867,0.0000298383,0.00005325256,0.000006982192,0.0002642102,0.0001228761,0.0001527383],"category_scores_gemma":[0.000217045,0.0001560139,0.00007518441,0.0001241572,0.0002765259,0.000003310598,0.0000568262,0.0001757662,0.00001276726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002107626,"about_ca_system_score_gemma":0.00004540436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004279933,"about_ca_topic_score_gemma":0.00000670876,"domain_scores_codex":[0.9987581,0.00007396082,0.0002372624,0.0003272851,0.0003297307,0.000273677],"domain_scores_gemma":[0.9992256,0.00002601548,0.00009651835,0.000452694,0.00009251121,0.0001066795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007775265,0.00003079487,0.0004522944,0.00008152458,0.00005612023,0.000002082508,0.00003717828,0.00005092273,0.9930235,6.867351e-7,0.001726642,0.003760685],"study_design_scores_gemma":[0.0006659764,0.0005255706,0.0001996549,0.00002508529,0.00001452899,0.00001458265,0.00005710727,0.0000358133,0.9905388,0.00001363456,0.007760748,0.0001484427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974039,0.0001936705,0.0008905935,0.0007511348,0.00006195992,0.0001096225,0.000008243474,0.00001942592,0.0005614632],"genre_scores_gemma":[0.9979937,0.00003432326,0.000102126,0.001272473,0.0003739327,0.00002308988,0.00005434021,0.00002271675,0.0001232903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006034106,"threshold_uncertainty_score":0.6362062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01455541092869917,"score_gpt":0.2746388894566501,"score_spread":0.2600834785279509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}