{"id":"W2042822986","doi":"10.1021/ml500322h","title":"Aptamer-Facilitated Cryoprotection of Viruses","year":2014,"lang":"en","type":"article","venue":"ACS Medicinal Chemistry Letters","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aptamer; Vesicular stomatitis virus; Virology; DNA; Viral load; Viral replication; Virus; Biology; Chemistry; Molecular biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001385917,0.0002198689,0.0001243751,0.0000971129,0.00009120315,0.0001342691,0.000185938,0.0002155199,0.0004883875],"category_scores_gemma":[0.0001155604,0.00009878579,0.0001504414,0.00005817209,0.0001427468,0.0001696062,0.0001873662,0.0002925288,0.0001447126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001441029,"about_ca_system_score_gemma":0.00009952805,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001954789,"about_ca_topic_score_gemma":0.0002780893,"domain_scores_codex":[0.9999141,0.00001503281,0.000005781196,0.00002568486,0.00002019202,0.00001922678],"domain_scores_gemma":[0.9999515,0.00001083535,0.00001368192,0.000006856371,0.00000895733,0.000008221245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002317101,0.000007742252,0.00003314202,0.00001218887,0.000002109651,0.00001242507,0.000008991162,0.0001661555,0.9986277,0.00007753665,0.00001672475,0.001012131],"study_design_scores_gemma":[0.000003127251,0.00007863218,0.000181948,9.584079e-7,0.000001989547,0.0000425942,0.000001918474,0.0006396496,0.9985914,0.00001792058,0.0004383911,0.000001498184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792606,0.001070498,0.01788459,0.00008141117,0.00003465982,0.00004652354,0.00009533083,0.0001165154,0.001409822],"genre_scores_gemma":[0.9897053,0.0003999783,0.00807408,0.00006031752,0.000006583391,0.00003319937,0.00009087901,0.00002075132,0.001608949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004883875,"threshold_uncertainty_score":0.001633883,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01455541092869917,"score_gpt":0.2746388894566501,"score_spread":0.2600834785279509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}