{"id":"W2042933244","doi":"10.1159/000218187","title":"HCO<sub>3</sub><sup>-</sup>-Dependent Impact of Na<sup>+</sup>,K<sup>+</sup>,2Cl<sup>-</sup> Cotransport in Vascular Smooth Muscle Excitation-Contraction Coupling","year":2009,"lang":"de","type":"article","venue":"Cellular Physiology and Biochemistry","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Bumetanide; Cotransporter; Chemistry; Endocrinology; Extracellular; Internal medicine; Depolarization; Contraction (grammar); Vascular smooth muscle; Cyclopiazonic acid; Intracellular; Inhibitory postsynaptic potential; Phenylephrine; Membrane potential; Biophysics; Sodium; Biochemistry; Smooth muscle; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","sts","open_science","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"category_scores_codex":[0.008753637,0.00991072,0.01280778,0.003696681,0.003591527,0.001033957,0.005576739,0.01059118,0.003806274],"category_scores_gemma":[0.003233642,0.01018989,0.006935921,0.006320985,0.0048772,0.002928212,0.001633207,0.008757434,0.002561239],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004844813,"about_ca_system_score_gemma":0.005111611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007022264,"about_ca_topic_score_gemma":0.000518104,"domain_scores_codex":[0.9563129,0.002948129,0.01114081,0.01146655,0.007079449,0.01105219],"domain_scores_gemma":[0.9711232,0.004031538,0.005921648,0.009552846,0.003781299,0.005589453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008595521,0.007257919,0.001839762,0.006450152,0.006410101,0.002399717,0.004942843,0.02898666,0.9126678,0.0004234225,0.01470528,0.005320852],"study_design_scores_gemma":[0.08593199,0.01049614,0.03114001,0.01331544,0.02169985,0.002130606,0.003374236,0.1064335,0.5791556,0.003954734,0.1157164,0.02665156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9050681,0.07279483,0.002733485,0.001077595,0.003222524,0.00803258,0.003237763,0.001638029,0.002195119],"genre_scores_gemma":[0.9326618,0.02985363,0.001626834,0.001604567,0.009670378,0.001140645,0.01716016,0.00171479,0.004567199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3335122,"threshold_uncertainty_score":0.9998035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01080147884621699,"score_gpt":0.2442892573622246,"score_spread":0.2334877785160076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}