{"id":"W2042944858","doi":"10.1016/j.cellsig.2011.08.012","title":"Regulation of TGFβ receptor trafficking and signaling by atypical protein kinase C","year":2011,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Protein kinase C; Cell biology; Signal transduction; Internalization; Receptor; Biology; Endocytic cycle; Phosphorylation; Transforming growth factor; Endocytosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001635048,0.0002807902,0.0001199958,0.0002643891,0.0003315273,0.0006849193,0.0002442475,0.0002938624,0.000991128],"category_scores_gemma":[0.0002120187,0.0001116035,0.0002093543,0.0001884893,0.0002946092,0.000464724,0.0003082643,0.0004508516,0.0003888482],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001096173,"about_ca_system_score_gemma":0.000418156,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001577079,"about_ca_topic_score_gemma":0.001426409,"domain_scores_codex":[0.9998614,0.00002180342,0.000008844641,0.00002158114,0.00002947992,0.00005701722],"domain_scores_gemma":[0.9998945,0.00001413652,0.00003043195,0.00001189452,0.00002120903,0.00002786843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004510379,0.00002266374,0.0005155214,0.00005109092,0.000006616832,0.0002388821,0.00002444135,0.0002362422,0.9912211,0.002404958,0.0001456731,0.004681875],"study_design_scores_gemma":[0.00005946836,0.0001207395,0.01729617,0.00001754735,0.0000193711,0.001241497,0.000129562,0.008604641,0.9625109,0.001428903,0.008547904,0.0000233314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9779596,0.009669499,0.005491446,0.0005220663,0.00008219991,0.00002398545,0.000229563,0.00008666571,0.005934929],"genre_scores_gemma":[0.9940561,0.002255948,0.001378882,0.00005605997,0.00001367374,0.00001176539,0.00011687,0.00001142509,0.002099329],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001577079,"threshold_uncertainty_score":0.007953346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01480630870564055,"score_gpt":0.2036437591947035,"score_spread":0.1888374504890629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}