{"id":"W2043043761","doi":"10.1074/jbc.m404954200","title":"Syntaxin-1A Inhibits Cardiac KATP Channels by Its Actions on Nucleotide Binding Folds 1 and 2 of Sulfonylurea Receptor 2A","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Toronto","funders":"","keywords":"Sulfonylurea receptor; Cell biology; Myocyte; Potassium channel; Chemistry; Biology; Internal medicine; Molecular biology; Endocrinology; Biochemistry; Protein subunit; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002139457,0.0003602624,0.0002734113,0.0001281033,0.0001802578,0.0002258104,0.0001937818,0.0002474012,0.0009268483],"category_scores_gemma":[0.000174528,0.0001010021,0.0003055994,0.0001014823,0.0002541113,0.0002497509,0.0001441657,0.000652992,0.0001792793],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002063483,"about_ca_system_score_gemma":0.0002332232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003506525,"about_ca_topic_score_gemma":0.0007633101,"domain_scores_codex":[0.9998114,0.00004844071,0.00003361151,0.00002611939,0.00003267964,0.00004779757],"domain_scores_gemma":[0.9999197,0.00001803884,0.00002054216,0.00000949375,0.000008557671,0.00002378231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005038473,0.0001201795,0.0002480877,0.00006749318,0.00001722397,0.00005683561,0.00002804245,0.00009545426,0.9967868,0.0001575734,0.0001107176,0.001807748],"study_design_scores_gemma":[0.0001493818,0.001448044,0.004322295,0.000009948441,0.00004016658,0.0002340894,0.00005257569,0.001755986,0.9890677,0.00009484748,0.002816914,0.000007924173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967175,0.001288419,0.0008470255,0.000203437,0.00004596876,0.00002192498,0.000104696,0.00004682733,0.0007242333],"genre_scores_gemma":[0.997323,0.0008580516,0.0006439792,0.00007997405,0.00001360622,0.00002958513,0.0001717988,0.000008125505,0.000871914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009268483,"threshold_uncertainty_score":0.003100634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02197982495898937,"score_gpt":0.2646008135093579,"score_spread":0.2426209885503685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}