{"id":"W2043081908","doi":"10.1182/blood-2001-11-0084","title":"Tumor necrosis factor-alpha expressed constitutively in erythroid cells or induced by erythropoietin has negative and stimulatory roles in normal erythropoiesis and erythroleukemia","year":2002,"lang":"en","type":"article","venue":"Blood","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Heart, Lung, and Blood Institute; University of Illinois at Chicago","keywords":"Autocrine signalling; Erythropoiesis; Erythropoietin receptor; Erythropoietin; Tumor necrosis factor alpha; Biology; Signal transduction; Cell biology; Cell culture; Cytokine; Cancer research; Endocrinology; Internal medicine; Immunology; Medicine; Anemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001268434,0.0002489186,0.0001615775,0.0001422756,0.00009526117,0.0002610317,0.0001112569,0.0001277256,0.0006538816],"category_scores_gemma":[0.0001602071,0.00009179716,0.0001160589,0.0001049309,0.0002279659,0.0001023998,0.0001247823,0.0002753524,0.0002459161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002018912,"about_ca_system_score_gemma":0.0001601295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002129127,"about_ca_topic_score_gemma":0.0002511659,"domain_scores_codex":[0.9998604,0.00002258955,0.00002089963,0.00002795482,0.00004416125,0.0000239612],"domain_scores_gemma":[0.9998658,0.0000263346,0.00003393745,0.0000279013,0.00001514436,0.00003083563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006764341,0.00001192256,0.0002798028,0.00001527018,0.000001423666,0.00007383307,0.000008051641,0.00002107315,0.9985178,0.00009708239,0.000009512238,0.0008966712],"study_design_scores_gemma":[0.00001674539,0.0002178539,0.006197767,0.000007725897,0.00001020658,0.0009066721,0.00001943871,0.0005534345,0.9887698,0.00007377022,0.003223583,0.000002998924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916003,0.003680419,0.002600257,0.000044127,0.00002334522,0.00002049376,0.0001732678,0.00006055076,0.001797377],"genre_scores_gemma":[0.9943286,0.001671393,0.001440612,0.0000153663,0.000009577891,0.000020391,0.0003638557,0.000009371995,0.002140914],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006538816,"threshold_uncertainty_score":0.00218749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02872423486421635,"score_gpt":0.2426733982988517,"score_spread":0.2139491634346353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}