{"id":"W2043114954","doi":"10.1111/j.1399-5448.2008.00464.x","title":"The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results","year":2008,"lang":"en","type":"article","venue":"Pediatric Diabetes","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":193,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; NIH Clinical Center; National Institutes of Health","keywords":"Medicine; Natural history; Type 2 diabetes; Autoantibody; Diabetes mellitus; Cohort; Internal medicine; Antibody; Type 1 diabetes; Prospective cohort study; Immunology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01129515,0.001020889,0.00169552,0.0007515434,0.001047937,0.001615904,0.001532389,0.00164752,0.007021128],"category_scores_gemma":[0.01093467,0.0007737406,0.0005253432,0.002469272,0.001229631,0.00143799,0.001357006,0.001077703,0.001435816],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001435496,"about_ca_system_score_gemma":0.003261628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002683355,"about_ca_topic_score_gemma":0.005619789,"domain_scores_codex":[0.9899642,0.007966184,0.0003705307,0.000587489,0.000811691,0.0002998344],"domain_scores_gemma":[0.9917691,0.00230114,0.002668164,0.0008839852,0.0009503342,0.001427277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3122722,0.004076384,0.5500131,0.004651001,0.001997399,0.0005458783,0.0006055567,0.001906006,0.001560629,0.005681826,0.0500223,0.06666761],"study_design_scores_gemma":[0.2889254,0.02810496,0.5620482,0.002827554,0.003614925,0.001744209,0.0008325221,0.005548713,0.00159176,0.00667938,0.09776808,0.0003143411],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8007874,0.03574725,0.006293981,0.009083334,0.001724166,0.05228431,0.05480786,0.000198786,0.03907297],"genre_scores_gemma":[0.7701707,0.01180163,0.02408655,0.006535708,0.00331792,0.1195105,0.03903873,0.0002068012,0.02533152],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01129515,"threshold_uncertainty_score":0.05973518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01498802275610935,"score_gpt":0.2264370647054099,"score_spread":0.2114490419493005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}