{"id":"W2043114954","doi":"10.1111/j.1399-5448.2008.00464.x","title":"The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results","year":2008,"lang":"en","type":"article","venue":"Pediatric Diabetes","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":193,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; NIH Clinical Center; National Institutes of Health","keywords":"Medicine; Natural history; Type 2 diabetes; Autoantibody; Diabetes mellitus; Cohort; Internal medicine; Antibody; Type 1 diabetes; Prospective cohort study; Immunology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005370339,0.0001484369,0.0002080102,0.00004028945,0.0001849092,0.000006605498,0.0002656737,0.00008093746,0.000001655613],"category_scores_gemma":[0.0006808137,0.00009408989,0.0000626228,0.0001809645,0.0001517204,0.000005261582,0.0001613072,0.0001007727,7.00247e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002529767,"about_ca_system_score_gemma":0.0003185738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006093046,"about_ca_topic_score_gemma":0.00001594158,"domain_scores_codex":[0.9986581,0.0002203662,0.0004152825,0.0002361197,0.0002124946,0.0002576297],"domain_scores_gemma":[0.9990397,0.0002136571,0.0003102587,0.0002567548,0.000141986,0.0000376141],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008389208,0.002071103,0.8927386,0.000136124,0.001217389,0.000001085261,0.008499893,0.0001853229,0.04404048,0.00001344624,0.03389198,0.01636567],"study_design_scores_gemma":[0.01373344,0.00422875,0.832681,0.00004026528,0.0005818621,5.574236e-7,0.002777662,0.0002420579,0.1143315,0.0001255892,0.03007348,0.001183765],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893901,0.009486419,0.000001571011,0.00001964263,0.0004963069,0.0003910988,0.000008284253,0.000006348426,0.0002002034],"genre_scores_gemma":[0.9991498,0.0003212975,0.0001289469,0.00003041628,0.0001347238,0.00002349241,0.00001399668,0.0000145865,0.0001827324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07029106,"threshold_uncertainty_score":0.3836874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01498802275610935,"score_gpt":0.2264370647054099,"score_spread":0.2114490419493005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}