{"id":"W2043117828","doi":"10.1387/ijdb.062253lw","title":"Soluble membrane-type 3 matrix metalloprioteinase causes changes in gene expression and increased gelatinase activity during Xenopus laevis development","year":2007,"lang":"en","type":"article","venue":"The International Journal of Developmental Biology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Xenopus; Matrix metalloproteinase; Extracellular matrix; Gelatinase; Cell biology; Embryo; Chordin; Gelatinase A; Fibronectin; Molecular biology; Gene expression; Embryogenesis; Gene; Gastrulation; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001678962,0.0004496383,0.0003133732,0.0003515986,0.0001460796,0.0004395688,0.0002203549,0.0005279933,0.001513221],"category_scores_gemma":[0.0001716327,0.0002630935,0.0003942607,0.0001335934,0.000334438,0.0002104797,0.0002019892,0.00068913,0.0004633627],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004927327,"about_ca_system_score_gemma":0.0002323018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001420354,"about_ca_topic_score_gemma":0.001300062,"domain_scores_codex":[0.9997175,0.00004539728,0.0000350515,0.00007113071,0.00006311961,0.00006771538],"domain_scores_gemma":[0.999598,0.0001156669,0.0001301413,0.00003744829,0.00002676709,0.00009197299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004862498,0.00001277893,0.00005249528,0.00001370376,0.000002606415,0.00005396995,0.00001307336,0.00002117301,0.9995677,0.00003422716,0.000009537417,0.0001701866],"study_design_scores_gemma":[0.00001740471,0.0003922296,0.004275758,0.000007372781,0.00001459511,0.0002681352,0.00003739183,0.0004602558,0.9931392,0.00002799285,0.001352426,0.000007216428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942265,0.001313821,0.002109818,0.0001193978,0.00004841758,0.00003567127,0.0007084882,0.0001586392,0.001279175],"genre_scores_gemma":[0.9902087,0.0007323701,0.001778575,0.00008398166,0.00001606595,0.00006710266,0.001023433,0.00007491027,0.006014866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001513221,"threshold_uncertainty_score":0.005062222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01268325408751418,"score_gpt":0.2666379750812814,"score_spread":0.2539547209937672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}