{"id":"W2043287555","doi":"10.4161/auto.29640","title":"FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"National Institute of General Medical Sciences; Cancer Research UK","keywords":"Folliculin; Autophagy; ULK1; Biology; Cell biology; BAG3; Phosphorylation; Cancer research; Protein kinase A; AMPK; Biochemistry; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001349719,0.0002920421,0.0004225439,0.0001078531,0.00008645095,0.0000420072,0.00007374123,0.0001174918,0.0001993998],"category_scores_gemma":[0.00002828499,0.0002241681,0.00006579339,0.00017875,0.0000865542,0.0001284685,0.00004517151,0.0001776011,0.00008042408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001273141,"about_ca_system_score_gemma":0.00004645961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001964382,"about_ca_topic_score_gemma":0.000006666871,"domain_scores_codex":[0.9985209,0.00003944858,0.0003004094,0.0004859874,0.0003313708,0.0003218632],"domain_scores_gemma":[0.9989822,0.00008674157,0.0001468426,0.0004309355,0.000107507,0.0002458112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001521024,0.001058136,0.005364315,0.00023662,0.0005813432,0.0001832506,0.001934657,0.00002305323,0.9514,0.001012137,0.01361715,0.02306835],"study_design_scores_gemma":[0.006773925,0.001567582,0.2618555,0.0002044107,0.000265647,0.0005416631,0.00003347166,0.008713519,0.7068737,0.00007438951,0.01276211,0.0003340266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928508,0.0009568436,0.001251354,0.0007105639,0.0001044745,0.0004729575,0.00001264241,0.0001447351,0.00349566],"genre_scores_gemma":[0.9924825,0.0000273056,0.001862777,0.001075226,0.00006522675,0.00002709002,0.0001345269,0.00005050575,0.00427488],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2564912,"threshold_uncertainty_score":0.914131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01081754424201174,"score_gpt":0.2297516420231299,"score_spread":0.2189340977811181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}