{"id":"W2043287555","doi":"10.4161/auto.29640","title":"FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation","year":2014,"lang":"en","type":"article","venue":"Autophagy","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"National Institute of General Medical Sciences; Cancer Research UK","keywords":"Folliculin; Autophagy; ULK1; Biology; Cell biology; BAG3; Phosphorylation; Cancer research; Protein kinase A; AMPK; Biochemistry; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007840229,0.0004923388,0.0002176268,0.0003554157,0.0003450459,0.0002886051,0.0002171438,0.0002938274,0.0007504585],"category_scores_gemma":[0.0001081408,0.0001900502,0.0003030537,0.0002256238,0.0002371771,0.000244973,0.0003522144,0.0001948159,0.0003583164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00101329,"about_ca_system_score_gemma":0.0002013867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001366961,"about_ca_topic_score_gemma":0.001723647,"domain_scores_codex":[0.9998777,0.00001152439,0.000008668478,0.0000382033,0.00003171245,0.00003221781],"domain_scores_gemma":[0.9999249,0.000004616665,0.00003667056,0.000004710118,0.000006788628,0.00002231236],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001179161,0.00000695954,0.0006631044,0.00003937505,0.000009241971,0.000196552,0.00001043809,0.00006099946,0.9979114,0.00006990982,0.00007171827,0.0008423551],"study_design_scores_gemma":[0.00003103867,0.00007623868,0.04924635,0.00001674382,0.00003160447,0.002763039,0.00004127842,0.002353402,0.9391258,0.0001448886,0.006153553,0.00001612966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934146,0.00282791,0.002154131,0.00009833917,0.00001892568,0.00001181083,0.0003438873,0.0001004485,0.001029841],"genre_scores_gemma":[0.9932891,0.0008702693,0.001948423,0.00007009879,0.000008716855,0.00002120517,0.001372544,0.00002814219,0.002391544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001366961,"threshold_uncertainty_score":0.007351995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01081754424201174,"score_gpt":0.2297516420231299,"score_spread":0.2189340977811181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}