{"id":"W2043360293","doi":"10.1016/j.jsbmb.2010.12.007","title":"Contribution to the development of inhibitors of 17β-hydroxysteroid dehydrogenase types 1 and 7: Key tools for studying and treating estrogen-dependent diseases","year":2010,"lang":"en","type":"review","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Estrogen; Enzyme; Estrone; Biology; Biochemistry; Dehydrogenase; Chemistry; Pharmacology; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009647356,0.001365004,0.001811024,0.001693058,0.0002935446,0.001099751,0.001325291,0.001593546,0.003424403],"category_scores_gemma":[0.0009695293,0.0004119515,0.0005985564,0.001635171,0.0007663001,0.001439944,0.0007883726,0.003750714,0.002924926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008488225,"about_ca_system_score_gemma":0.001148927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009026633,"about_ca_topic_score_gemma":0.001962095,"domain_scores_codex":[0.9997694,0.00003371566,0.00002916984,0.00004341853,0.00009694449,0.00002742303],"domain_scores_gemma":[0.9994769,0.0002148639,0.00007266038,0.00002050815,0.0001546818,0.00006045459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002174085,0.0001653014,0.0001503829,0.008975795,0.0001322697,0.0003183595,0.00004029432,0.0005939109,0.006856206,0.006523666,0.043989,0.9320374],"study_design_scores_gemma":[0.00008275616,0.0001383995,0.0004771386,0.0009133108,0.0001522026,0.001006356,0.00002111724,0.0001227352,0.001950189,0.001721522,0.9933923,0.00002210709],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001796497,0.9971853,0.0006001614,0.0004486783,0.0004953068,0.000009435698,0.0000319426,0.00001498311,0.001034633],"genre_scores_gemma":[0.0009656132,0.996614,0.0006281712,0.0003952226,0.0003400006,0.0000118247,0.00005396825,0.000003312163,0.0009876875],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003424403,"threshold_uncertainty_score":0.01145577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01203577488849026,"score_gpt":0.2884112749234223,"score_spread":0.2763755000349321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}