{"id":"W2043379423","doi":"10.1074/jbc.m501034200","title":"Structural and Biochemical Analysis Reveal Pirins to Possess Quercetinase Activity","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Porphyrin Metabolism and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Escherichia coli; Biochemistry; Biology; Gene product; Gene; Chemistry; Cell biology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006217293,0.0001872765,0.0001132724,0.00007908448,0.00009422914,0.0001996042,0.0001308117,0.0001649325,0.0007910821],"category_scores_gemma":[0.0001338128,0.0000744694,0.0001432689,0.0001236386,0.000129648,0.00011889,0.0001039659,0.0002853329,0.0002189595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000163519,"about_ca_system_score_gemma":0.00008862474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005192449,"about_ca_topic_score_gemma":0.0004649921,"domain_scores_codex":[0.999972,0.000004418091,0.000001785921,0.000005862013,0.000009334242,0.000006645306],"domain_scores_gemma":[0.9999386,0.00001104877,0.00001906699,0.000006502588,0.000006774118,0.00001799965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001260057,0.00002363825,0.0008717658,0.00002555978,0.000006932667,0.000192572,0.00001349092,0.0001755486,0.9967598,0.0001435742,0.00003020059,0.001631005],"study_design_scores_gemma":[0.00003764836,0.0003948486,0.02890708,0.000005792414,0.0000302908,0.002104623,0.00005475412,0.003170761,0.9591411,0.0002069436,0.005935308,0.00001085755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978822,0.0003385459,0.001007882,0.00006255667,0.00000405854,0.000005768475,0.0001703131,0.00001520007,0.0005135447],"genre_scores_gemma":[0.9958615,0.000244692,0.001917297,0.00002483535,0.000005832791,0.000004162839,0.001007272,0.000007274681,0.0009271645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007910821,"threshold_uncertainty_score":0.002646387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01272785705085792,"score_gpt":0.2731978641296667,"score_spread":0.2604700070788088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}