{"id":"W2043395973","doi":"10.1182/blood-2002-09-2888","title":"Combined carrier status of prothrombin 20210A and factor XIII-A Leu34 alleles as a strong risk factor for myocardial infarction: evidence of a gene-gene interaction","year":2003,"lang":"en","type":"article","venue":"Blood","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Allele; Penetrance; Risk factor; Internal medicine; Population; Gastroenterology; Biology; Factor V Leiden; Allele frequency; Genetics; Medicine; Gene; Thrombosis; Venous thrombosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006813363,0.0004181895,0.0003471301,0.001154568,0.0003588269,0.0005542989,0.0004416512,0.0005582538,0.002268362],"category_scores_gemma":[0.002755971,0.0002981847,0.000306103,0.0008076156,0.0006884095,0.0002044157,0.0003391157,0.0004664671,0.0002409622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002285522,"about_ca_system_score_gemma":0.000272607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007446131,"about_ca_topic_score_gemma":0.007562664,"domain_scores_codex":[0.9994016,0.0002007234,0.00005440454,0.0001262574,0.0001245988,0.00009233701],"domain_scores_gemma":[0.9974304,0.0009882402,0.0008682405,0.0001436998,0.0001632224,0.0004061642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006150071,0.00004088314,0.9937974,0.00001158138,0.0001535523,0.0005338827,0.0000628245,0.00002499925,0.003120261,0.00002042201,0.00006030393,0.001558995],"study_design_scores_gemma":[0.00001747619,0.000174162,0.9972987,0.00000475568,0.0001891326,0.001672263,0.00005849724,0.0002271083,0.0002462502,0.0000208568,0.00008687673,0.000003958081],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992887,0.0003162329,0.00006688526,0.00003082121,0.000004550445,0.000002142824,0.00004252297,0.000002462913,0.0002456952],"genre_scores_gemma":[0.9996119,0.00009011211,0.00009408052,0.0000161381,0.00001719984,0.000002283702,0.00006458529,0.000001425768,0.0001022505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007446131,"threshold_uncertainty_score":0.01480561,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04623471223346648,"score_gpt":0.3131978625599723,"score_spread":0.2669631503265059,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}