{"id":"W2043401170","doi":"10.1016/j.coi.2012.07.001","title":"The role of induced pluripotent stem cells in research and therapy of primary immunodeficiencies","year":2012,"lang":"en","type":"review","venue":"Current Opinion in Immunology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Manton Foundation","keywords":"Induced pluripotent stem cell; Reprogramming; Embryonic stem cell; Stem cell; Biology; Induced stem cells; Cell biology; Immunology; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001313731,0.0009450989,0.001618779,0.001148036,0.0002385822,0.0009990685,0.001298981,0.001498342,0.002673105],"category_scores_gemma":[0.001043555,0.000263652,0.0004270066,0.001430659,0.0008625856,0.001706105,0.0008601607,0.00305487,0.001665127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007128949,"about_ca_system_score_gemma":0.0008916066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005733983,"about_ca_topic_score_gemma":0.001212288,"domain_scores_codex":[0.9997358,0.00004919324,0.00003025542,0.00004194032,0.0001132434,0.00002956112],"domain_scores_gemma":[0.9994302,0.0003134823,0.00005048613,0.00001679316,0.0001277768,0.00006125963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001215831,0.00005875484,0.0001123574,0.008637601,0.00007092141,0.0002462578,0.00003700606,0.0004086093,0.003698708,0.007109329,0.04543965,0.9340592],"study_design_scores_gemma":[0.00004405626,0.00007553195,0.0004279866,0.001505688,0.0001025917,0.0007741061,0.00004048289,0.0001300657,0.0008250142,0.003933992,0.9921221,0.00001840576],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008092608,0.9976128,0.0003354782,0.0007040461,0.0006538377,0.000003543113,0.00001471577,0.000007322886,0.0005872899],"genre_scores_gemma":[0.0006417947,0.9975236,0.0003337039,0.00042367,0.0006100542,0.000006384688,0.00002661127,0.000001877693,0.0004322161],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002673105,"threshold_uncertainty_score":0.008942485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1989572558476207,"score_gpt":0.4041138391606685,"score_spread":0.2051565833130478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}