{"id":"W2043470730","doi":"10.1016/j.jinorgbio.2011.05.012","title":"Up-regulation of NF-kB-sensitive miRNA-125b and miRNA-146a in metal sulfate-stressed human astroglial (HAG) primary cell cultures","year":2011,"lang":"en","type":"article","venue":"Journal of Inorganic Biochemistry","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Surrey Place Centre","funders":"National Eye Institute; National Institute on Aging; National Institutes of Health","keywords":"Chemistry; microRNA; Reactive oxygen species; NF-κB; Immune system; Antioxidant; Resveratrol; Biochemistry; Cell biology; Molecular biology; Gene; Signal transduction; Biology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002931106,0.0002941831,0.0005282548,0.0003272484,0.0003184713,0.0004494262,0.0001725651,0.000258817,0.001696269],"category_scores_gemma":[0.0002716304,0.0002791851,0.0005411392,0.0002644044,0.0002761713,0.0002341365,0.0002586613,0.0006781197,0.0007346979],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003118356,"about_ca_system_score_gemma":0.0003625895,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001335645,"about_ca_topic_score_gemma":0.002477924,"domain_scores_codex":[0.9996591,0.00003742805,0.00006468208,0.00008719928,0.00007837759,0.00007318865],"domain_scores_gemma":[0.9997931,0.00005333775,0.00003280442,0.00003002908,0.0000450166,0.00004567661],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002131236,0.00002997593,0.0001706648,0.0000361872,0.000007349408,0.00003546914,0.00004853118,0.00002474073,0.9987856,0.00005252809,0.00006007793,0.0005357065],"study_design_scores_gemma":[0.00001898014,0.0002490432,0.003945829,0.000004278272,0.00002596313,0.0001048152,0.0000531182,0.00060607,0.9935275,0.00003581402,0.001421859,0.000006764998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923604,0.001589181,0.002787378,0.000108059,0.0001107313,0.0000397671,0.00104803,0.000121517,0.00183506],"genre_scores_gemma":[0.9865898,0.0007543215,0.005461635,0.0001037306,0.00002721437,0.0001258663,0.001950687,0.00004188094,0.004944903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001696269,"threshold_uncertainty_score":0.005674541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007892610536153538,"score_gpt":0.2209466407278449,"score_spread":0.2130540301916914,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}