{"id":"W2043507805","doi":"10.1007/s10555-005-6192-2","title":"Role of antibody-dependent cell-mediated cytotoxicity in the efficacy of therapeutic anti-cancer monoclonal antibodies","year":2005,"lang":"en","type":"review","venue":"Cancer and Metastasis Reviews","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":193,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Antibody-dependent cell-mediated cytotoxicity; Monoclonal antibody; Antibody; Cancer; Cancer cell; Cytotoxicity; Cancer research; Immunology; Immune system; In vivo; Medicine; In vitro; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00149807,0.0007244888,0.005077618,0.0004076739,0.00008225925,0.00002333399,0.000548749,0.0002579669,0.0004474507],"category_scores_gemma":[0.0001052,0.0003870253,0.001175461,0.0008180241,0.0004110665,0.00007956026,0.0001671927,0.0008549905,0.00002161978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009055017,"about_ca_system_score_gemma":0.0005737274,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000451027,"about_ca_topic_score_gemma":0.0000717898,"domain_scores_codex":[0.9953405,0.0007485351,0.001910641,0.0006553463,0.000770849,0.0005741665],"domain_scores_gemma":[0.9973894,0.0006239146,0.001001757,0.0006455322,0.0001604738,0.0001789107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009737256,0.0004903098,0.001380854,0.03341854,0.0005068948,0.00001026445,0.0002343813,8.433294e-7,0.00151836,0.00005262303,0.0002304961,0.9620591],"study_design_scores_gemma":[0.0008293916,0.0001504673,0.002479382,0.01224232,0.002254402,0.0000319975,0.00005699851,0.000007373518,0.0007099389,0.000007493683,0.9808819,0.0003483577],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007592394,0.9876583,0.000002696306,0.000136408,0.00008053154,0.002964184,0.0008617934,0.000009647026,0.000694001],"genre_scores_gemma":[0.001502153,0.9967717,0.000136776,0.0001963317,0.0003113791,0.0003800871,0.0002313998,0.00005457951,0.0004155948],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9806514,"threshold_uncertainty_score":0.9998581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1028875700460999,"score_gpt":0.4296491712656157,"score_spread":0.3267616012195158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}