{"id":"W2043541147","doi":"10.1107/s1744309111021105","title":"Expression, purification and preliminary crystallographic analysis of Rv3002c, the regulatory subunit of acetolactate synthase (IlvH) from<i>Mycobacterium tuberculosis</i>","year":2011,"lang":"en","type":"article","venue":"Acta Crystallographica Section F Structural Biology and Crystallization Communications","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Isoleucine; Mycobacterium tuberculosis; Acetolactate synthase; Valine; Recombinant DNA; Biosynthesis; Protein subunit; Biology; Cloning (programming); Enzyme; Microbiology; ATP synthase; Leucine; Biochemistry; Tuberculosis; Amino acid; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004650218,0.0005426891,0.0004511958,0.0003607176,0.0003980064,0.0005426195,0.0005569657,0.0004761996,0.000692638],"category_scores_gemma":[0.0006221469,0.0001895259,0.0004796418,0.0007763266,0.000266177,0.00026087,0.000213488,0.001072164,0.0008795112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008518359,"about_ca_system_score_gemma":0.000618048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005680367,"about_ca_topic_score_gemma":0.004984284,"domain_scores_codex":[0.9997389,0.00004117662,0.00002606965,0.00004279952,0.0001036322,0.00004740941],"domain_scores_gemma":[0.9997706,0.0000436371,0.00003525539,0.00003161644,0.00006726162,0.0000516817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003509627,0.0001903925,0.00104102,0.0002100695,0.00002455051,0.0004594634,0.000106503,0.000755495,0.9878114,0.0003921872,0.002055617,0.006602544],"study_design_scores_gemma":[0.00008917537,0.0002538532,0.01333924,0.00002280727,0.00005960006,0.001442738,0.0001407493,0.003516635,0.9530951,0.0002220851,0.02777652,0.00004126982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9548401,0.00773479,0.01588407,0.001646179,0.0002639331,0.0002846605,0.01386776,0.0003642136,0.005114349],"genre_scores_gemma":[0.8591562,0.00824248,0.04136575,0.0003855228,0.00009627681,0.000177458,0.08075864,0.0002449567,0.009572776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005680367,"threshold_uncertainty_score":0.0112946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01648278533395982,"score_gpt":0.2571608367567235,"score_spread":0.2406780514227636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}