{"id":"W2043541147","doi":"10.1107/s1744309111021105","title":"Expression, purification and preliminary crystallographic analysis of Rv3002c, the regulatory subunit of acetolactate synthase (IlvH) from<i>Mycobacterium tuberculosis</i>","year":2011,"lang":"en","type":"article","venue":"Acta Crystallographica Section F Structural Biology and Crystallization Communications","topic":"Biochemical and Molecular Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Isoleucine; Mycobacterium tuberculosis; Acetolactate synthase; Valine; Recombinant DNA; Biosynthesis; Protein subunit; Biology; Cloning (programming); Enzyme; Microbiology; ATP synthase; Leucine; Biochemistry; Tuberculosis; Amino acid; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028013,0.000224199,0.0003148455,0.0003518457,0.0003479568,0.00001949888,0.0005225824,0.0003697405,0.00004374601],"category_scores_gemma":[0.0001114951,0.0001755116,0.000181217,0.0009134708,0.001590079,0.00003100984,0.0004675515,0.0002283414,3.360606e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000618513,"about_ca_system_score_gemma":0.00003371084,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000208648,"about_ca_topic_score_gemma":0.000194985,"domain_scores_codex":[0.9982088,0.000482809,0.0005333732,0.0004355097,0.0001334502,0.0002061139],"domain_scores_gemma":[0.9978214,0.0001168618,0.0003991571,0.001201853,0.0003546387,0.0001060842],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002491722,0.0000694418,0.03233347,0.00002935927,0.0007200158,1.295596e-7,0.0002992773,0.000005167994,0.9653869,0.0006200576,0.00002977529,0.0002572117],"study_design_scores_gemma":[0.0008728734,0.0007391082,0.8287084,0.00005906876,0.001507769,0.00002397183,0.0009089998,0.0008041599,0.157058,0.00326455,0.005496837,0.0005562503],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946571,0.002596738,0.00170802,0.0002795347,0.00004427391,0.0003349506,0.0002220846,0.00002176157,0.0001355417],"genre_scores_gemma":[0.9918044,0.004780598,0.001016207,0.00006791486,0.00002461687,0.00005723233,0.002219269,0.00001756148,0.00001225473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8083289,"threshold_uncertainty_score":0.7157155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01648278533395982,"score_gpt":0.2571608367567235,"score_spread":0.2406780514227636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}