{"id":"W2043557765","doi":"10.1038/ncomms3593","title":"Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F","year":2013,"lang":"en","type":"article","venue":"Nature Communications","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Canada Research Chairs","funders":"Basic Energy Sciences; National Center for Research Resources; Canadian Institutes of Health Research; National Institutes of Health; University of Toronto; U.S. Department of Energy","keywords":"Human immunodeficiency virus (HIV); DNA; Computational biology; Genetics; Virology; Chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001707086,0.0002447946,0.0002769505,0.0002141177,0.0006008424,0.0004549775,0.0003598532,0.0004731761,0.006276594],"category_scores_gemma":[0.0004403999,0.0001769934,0.000285522,0.0001912491,0.0003888288,0.0002400004,0.0002531339,0.0007749471,0.0008410424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007960769,"about_ca_system_score_gemma":0.0005028007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008963453,"about_ca_topic_score_gemma":0.01271695,"domain_scores_codex":[0.9998293,0.00002632696,0.000007047673,0.00002318131,0.00004174678,0.00007247495],"domain_scores_gemma":[0.999711,0.00009703104,0.00003989322,0.00001306489,0.00003288667,0.0001060736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007257871,0.0001165338,0.004238493,0.00003887501,0.00002516044,0.0004074923,0.0001013234,0.0009550133,0.9866679,0.002002985,0.0003461627,0.004374253],"study_design_scores_gemma":[0.0002218146,0.000886783,0.1233926,0.00005525148,0.00009920003,0.002301673,0.0005824435,0.02540772,0.8370515,0.002563084,0.007305715,0.0001322269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968659,0.0002670105,0.0009809075,0.00006479779,0.00001337438,0.000009178754,0.00007038955,0.00003011484,0.001698216],"genre_scores_gemma":[0.9990566,0.00002707141,0.0002161063,0.00002681198,0.000004851855,0.000002357996,0.00005705267,0.000007832577,0.0006012502],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008963453,"threshold_uncertainty_score":0.02099735,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02308381265743193,"score_gpt":0.3185571353927468,"score_spread":0.2954733227353149,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}