{"id":"W2043703144","doi":"10.1074/jbc.m610161200","title":"Regulation of ADAMTS9 Secretion and Enzymatic Activity by Its Propeptide","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Furin; Protein precursor; Proprotein convertase; Secretion; Zymogen; Glycosylation; Metalloproteinase; Versican; Proprotein Convertases; Secretory pathway; Biochemistry; Chemistry; Cell biology; Biology; Matrix metalloproteinase; Enzyme; Endoplasmic reticulum; Proteoglycan; Extracellular matrix; Golgi apparatus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001643786,0.0002965177,0.0002003223,0.0001298302,0.00012553,0.0004517148,0.0001258485,0.0002145595,0.0007474347],"category_scores_gemma":[0.0001370139,0.0001264728,0.0002317991,0.00009345733,0.0002521774,0.0002022098,0.0001636789,0.0004485651,0.0003255118],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000268425,"about_ca_system_score_gemma":0.0001796953,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002926158,"about_ca_topic_score_gemma":0.0002836615,"domain_scores_codex":[0.9997573,0.00005368642,0.00003350441,0.00003470689,0.00006861506,0.00005215023],"domain_scores_gemma":[0.99985,0.00002981223,0.00004743123,0.00001687864,0.00002420809,0.00003157565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008841802,0.00001314141,0.0001807354,0.00001622695,0.000003068592,0.00008148667,0.000008714344,0.00003430093,0.9990338,0.00005547937,0.00001709305,0.0004676162],"study_design_scores_gemma":[0.00001218825,0.0001030772,0.004067787,0.000003497962,0.00000755967,0.000197989,0.00002805372,0.0007085992,0.9934363,0.00003264497,0.001399284,0.000002925437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953228,0.001433452,0.002056036,0.00009105745,0.00002841909,0.00002487286,0.0002121822,0.00003034891,0.0008007594],"genre_scores_gemma":[0.9951528,0.0008476963,0.002041395,0.00004163117,0.00001318782,0.00002487941,0.0003910769,0.00001234883,0.001475093],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007474347,"threshold_uncertainty_score":0.002500415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02024128056355301,"score_gpt":0.2824832794248274,"score_spread":0.2622419988612744,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}