{"id":"W2043759663","doi":"10.1111/exd.12597","title":"Skin manifestations of mitochondrial dysfunction: more important than previously thought","year":2015,"lang":"en","type":"letter","venue":"Experimental Dermatology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Institutes of Health; NIHR Newcastle Biomedical Research Centre; Newcastle University; NIHR Biomedical Research Centre, Royal Marsden NHS Foundation Trust/Institute of Cancer Research","keywords":"Mitochondrial DNA; Context (archaeology); Disease; Mitochondrion; Biology; Epidermolysis bullosa simplex; Mitochondrial disease; Genetics; Medicine; Gene; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001562719,0.0008318222,0.00228955,0.001793089,0.0008971718,0.003196944,0.0009843919,0.003664501,0.005867791],"category_scores_gemma":[0.003221371,0.0002518251,0.0006369514,0.001513676,0.003426617,0.006573644,0.002193585,0.004236352,0.001514289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007934535,"about_ca_system_score_gemma":0.0008206016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001055553,"about_ca_topic_score_gemma":0.001304726,"domain_scores_codex":[0.9990933,0.0002258041,0.0001332164,0.0001824118,0.0002620967,0.000103053],"domain_scores_gemma":[0.996845,0.001649229,0.0003902686,0.0001868785,0.0006676578,0.0002611065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006079709,0.0001414062,0.01228376,0.01444337,0.0003342156,0.02135205,0.003237227,0.0003510551,0.007680223,0.03965531,0.08922816,0.8106853],"study_design_scores_gemma":[0.00006416802,0.0004709033,0.02353776,0.01596887,0.0003479756,0.1259957,0.005908825,0.000398914,0.002703772,0.06640539,0.7579251,0.0002725791],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.005528509,0.9531487,0.001798555,0.03134251,0.004034534,0.00001338462,0.0001240071,0.00006006859,0.003949803],"genre_scores_gemma":[0.06258636,0.886871,0.001791282,0.01831385,0.026355,0.00002592958,0.0002233583,0.00005274569,0.003780536],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.005867791,"threshold_uncertainty_score":0.01962966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01527423055118177,"score_gpt":0.2748536476178787,"score_spread":0.259579417066697,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}