{"id":"W2043768128","doi":"10.1042/cs20110562","title":"Free radical biology of the cardiovascular system","year":2012,"lang":"en","type":"review","venue":"Clinical Science","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute","keywords":"Peroxynitrite; Superoxide; Enos; Antioxidant; Reactive oxygen species; Oxidative stress; Biochemistry; Reactive nitrogen species; Free-radical theory of aging; Chemistry; Sirtuin; Radical; Mitochondrion; Superoxide dismutase; Enzyme; Nitric oxide synthase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006917214,0.000196989,0.002344483,0.00008515092,0.00008671472,0.000005867608,0.001294093,0.0003882769,0.00001689552],"category_scores_gemma":[0.004012911,0.00008989047,0.002239199,0.0009914507,0.00261188,0.00003140559,0.0005411883,0.0006580838,0.00009425865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001014529,"about_ca_system_score_gemma":0.0009540679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002888863,"about_ca_topic_score_gemma":2.283499e-7,"domain_scores_codex":[0.9970523,0.0005676538,0.0009525407,0.0004727085,0.0005462197,0.0004086464],"domain_scores_gemma":[0.9960889,0.001189222,0.0003191675,0.002008333,0.0000790045,0.0003153295],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000002564095,0.00005550867,0.0003476503,0.007828842,0.0001598504,0.000005538197,0.000004446477,5.140924e-8,0.000002008001,0.0006147496,0.000116521,0.9908623],"study_design_scores_gemma":[0.0003314303,0.00009300915,0.0001877015,0.005810915,0.002682412,0.0001638601,0.000004399127,0.000005250839,0.000006026231,0.0000127586,0.9906003,0.0001019286],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001677602,0.9946456,0.00005246506,0.00002879623,0.002142791,0.0006941168,0.0000171777,0.00002865059,0.002222632],"genre_scores_gemma":[0.003269218,0.9952664,0.0002238937,0.00004725352,0.001060123,0.00002187532,0.000001935507,0.00001585891,0.00009346876],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9907603,"threshold_uncertainty_score":0.9623581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1523375726655015,"score_gpt":0.4302266592239556,"score_spread":0.2778890865584541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}