{"id":"W2043774033","doi":"10.1111/j.1399-0004.2010.01414_3.x","title":"Down's syndrome patients are less likely to develop cancer","year":2010,"lang":"en","type":"letter","venue":"Clinical Genetics","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute","funders":"","keywords":"Calcineurin; Internal medicine; Medicine; Endocrinology; Cancer; Cancer research; Genetics; Oncology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003410646,0.0002937938,0.0005996319,0.0003713862,0.0003588267,0.0004850345,0.0002185144,0.001849935,0.005303469],"category_scores_gemma":[0.003659829,0.000126914,0.0002271549,0.0003701684,0.0002860482,0.0004421078,0.0001873812,0.001238759,0.001120048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001806644,"about_ca_system_score_gemma":0.000122682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008472517,"about_ca_topic_score_gemma":0.0009347738,"domain_scores_codex":[0.9997889,0.00006202432,0.00001777376,0.00004289528,0.00005010272,0.00003835202],"domain_scores_gemma":[0.9990053,0.0004796427,0.0001596693,0.00007920073,0.0001118265,0.0001643474],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002421594,0.0002878286,0.6690031,0.0004160394,0.0002622588,0.04563407,0.00057512,0.0003678636,0.0222499,0.00510311,0.1072231,0.1464561],"study_design_scores_gemma":[0.0003863488,0.0009234511,0.6714603,0.0001857171,0.0001972306,0.1480353,0.0005851943,0.001133422,0.003196842,0.007109247,0.1666692,0.0001177908],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.7774775,0.01763749,0.002836301,0.1501364,0.006834973,0.00006335173,0.002369112,0.0001931416,0.04245188],"genre_scores_gemma":[0.9483132,0.005692345,0.001061851,0.02803446,0.004481574,0.00003900586,0.0007357634,0.00004026999,0.01160156],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.005303469,"threshold_uncertainty_score":0.01774186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05500180172933337,"score_gpt":0.3360998904888584,"score_spread":0.281098088759525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}