{"id":"W2043788452","doi":"10.1139/o10-110","title":"Gene insulation. Part I: natural strategies in yeast and <i>Drosophila</i>","year":2010,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biology; Enhancer; RNA polymerase III; Heterochromatin; Genetics; RNA polymerase II; Chromatin; Gene; Drosophila melanogaster; Transcription (linguistics); RNA polymerase; RNA; Promoter; Gene expression","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003137217,0.0008306226,0.0008111873,0.001378008,0.0002454797,0.000656132,0.0006628762,0.0008430041,0.002189179],"category_scores_gemma":[0.0003227714,0.0002764635,0.000283826,0.00156989,0.001001405,0.001340156,0.0005481006,0.001309194,0.003088983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007311626,"about_ca_system_score_gemma":0.00052024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009789137,"about_ca_topic_score_gemma":0.001392933,"domain_scores_codex":[0.9998533,0.00001621451,0.00002115017,0.00004524683,0.00005200543,0.00001218913],"domain_scores_gemma":[0.9998704,0.0000631189,0.00001950583,0.000009076921,0.00002489612,0.00001288203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004320354,0.00004097555,0.0001463374,0.008002087,0.00003411355,0.0001982436,0.00008092596,0.0004483856,0.006593674,0.01111846,0.03082114,0.9424723],"study_design_scores_gemma":[0.000004841423,0.000033104,0.0003800164,0.0005500503,0.00001348509,0.0007010006,0.00003168624,0.00003904453,0.001220741,0.001634239,0.9953821,0.000009679648],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001752677,0.9960696,0.0005723364,0.0001818662,0.0003722456,0.000005139322,0.00002370045,0.00001403298,0.002585904],"genre_scores_gemma":[0.001449681,0.9943255,0.0007202291,0.0004587985,0.0002712781,0.00001483055,0.00007418175,0.000006841556,0.002678795],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002189179,"threshold_uncertainty_score":0.007323563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009855581152011893,"score_gpt":0.2969414988729742,"score_spread":0.2870859177209623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}