{"id":"W2043816982","doi":"10.1074/jbc.m115.643189","title":"The Chromatin Regulator Brpf1 Regulates Embryo Development and Cell Proliferation","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; National Research Council Canada; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Chromatin; Cell biology; Bromodomain; Embryonic stem cell; Genetics; Histone; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001143293,0.0003186381,0.0001808269,0.0003165368,0.000237319,0.0003122914,0.0002128752,0.0002672167,0.001204025],"category_scores_gemma":[0.0001458314,0.0001853158,0.0001380839,0.0001844855,0.0002568999,0.0002897083,0.0002602974,0.000278918,0.0006146274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003090282,"about_ca_system_score_gemma":0.0001615243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004749527,"about_ca_topic_score_gemma":0.0006222202,"domain_scores_codex":[0.9999123,0.0000101253,0.000003401165,0.00003258354,0.00002577924,0.00001586097],"domain_scores_gemma":[0.9999331,0.000007292508,0.00002733753,0.000005667659,0.000009409266,0.00001716262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004564876,0.000003581801,0.0005925512,0.00002906916,0.000002729327,0.00005083665,0.00001027847,0.00008485839,0.9944208,0.0003676651,0.0001001895,0.004291761],"study_design_scores_gemma":[0.00003439563,0.0001538615,0.05518208,0.00002749764,0.00002665971,0.001014318,0.0000475074,0.002415085,0.9147274,0.001238073,0.02511539,0.00001784847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9289474,0.03131278,0.02581891,0.0004997156,0.00007889498,0.00004135771,0.001505352,0.001100351,0.01069533],"genre_scores_gemma":[0.9862321,0.005247238,0.003570826,0.00007536166,0.00002715127,0.00001738138,0.0006952163,0.00006037679,0.004074283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001204025,"threshold_uncertainty_score":0.004027843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01243322068368286,"score_gpt":0.2149402423127176,"score_spread":0.2025070216290347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}