{"id":"W2043825921","doi":"10.1038/nm1753","title":"Functional roles for C5a receptors in sepsis","year":2008,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":381,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute","keywords":"Blockade; Sepsis; C5a receptor; Receptor; Medicine; Immunology; Biology; Immune system; Internal medicine; Complement system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006973344,0.0007103318,0.0002693589,0.000603334,0.0004191957,0.0008409919,0.0003723238,0.001179003,0.001106214],"category_scores_gemma":[0.0004526972,0.0001847839,0.0003160266,0.0002287351,0.000989889,0.0005501788,0.0003608069,0.001285858,0.0002676341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001081529,"about_ca_system_score_gemma":0.0005851386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001346738,"about_ca_topic_score_gemma":0.0006492705,"domain_scores_codex":[0.9997707,0.00008358479,0.00001843105,0.00002483718,0.00004362287,0.00005873789],"domain_scores_gemma":[0.9997885,0.00004885775,0.00003904283,0.000020349,0.00003552922,0.00006777672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004324086,0.0001356088,0.001847283,0.0006102935,0.00009615959,0.002806855,0.000151438,0.002193223,0.9025247,0.03097166,0.002218843,0.05211978],"study_design_scores_gemma":[0.0004760058,0.003274229,0.05333145,0.0005844584,0.0003650902,0.01058473,0.0007517515,0.01082897,0.8072887,0.02738039,0.08498171,0.0001524562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5731008,0.3756534,0.01492254,0.01612788,0.001165407,0.00007253991,0.0004665043,0.0001770058,0.01831389],"genre_scores_gemma":[0.9569982,0.03411522,0.004087579,0.0008941176,0.0002789019,0.00004018304,0.0002092661,0.00001193921,0.003364593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001346738,"threshold_uncertainty_score":0.007847071,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01261521190181303,"score_gpt":0.2580618669746788,"score_spread":0.2454466550728657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}