{"id":"W2043890741","doi":"10.1074/jbc.m203593200","title":"Phosphorylation-independent Regulation of Metabotropic Glutamate Receptor Signaling by G Protein-coupled Receptor Kinase 2","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institutes of Health Research; Western University","funders":"","keywords":"Metabotropic glutamate receptor 1; Metabotropic glutamate receptor; Beta adrenergic receptor kinase; G protein-coupled receptor kinase; Phosphorylation; Metabotropic glutamate receptor 6; Cell biology; Biology; Biochemistry; G protein-coupled receptor; Metabotropic glutamate receptor 5; Signal transduction; Chemistry; Receptor; Glutamate receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004470291,0.0001923964,0.00036458,0.00003196544,0.00004238135,0.00001811184,0.0002405901,0.0003477612,0.002411643],"category_scores_gemma":[0.0002020011,0.0001505969,0.0002195763,0.0001143091,0.00006129484,0.00001106441,0.00004765802,0.0002276128,0.000006076079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004261437,"about_ca_system_score_gemma":0.00002716066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003349742,"about_ca_topic_score_gemma":1.865533e-7,"domain_scores_codex":[0.9984019,0.00007431424,0.0007755845,0.0002560156,0.000260295,0.0002318287],"domain_scores_gemma":[0.9988166,0.00002316178,0.000673619,0.0001696934,0.0002040027,0.0001129155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000203696,0.0001753346,0.0004781061,0.0000347974,0.00004537089,0.000002493965,0.00001740126,0.0001841238,0.9977593,0.00000776562,0.0004052013,0.0006864106],"study_design_scores_gemma":[0.0007811724,0.0003607651,0.00009296757,0.00007899046,0.00001227658,0.000008881501,0.00005746646,0.0002112311,0.9949629,0.00009449918,0.003165871,0.000173017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949925,0.00339523,0.001149137,0.00009285059,0.0001387509,0.0001344561,0.00001597846,0.000005311589,0.00007576324],"genre_scores_gemma":[0.9962445,0.000361718,0.002631087,0.00002396194,0.0002851484,0.000007813694,0.00004639101,0.00001503157,0.0003842974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003033512,"threshold_uncertainty_score":0.9985003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01410504479317585,"score_gpt":0.216946670296607,"score_spread":0.2028416255034311,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}