{"id":"W2043908348","doi":"10.1523/jneurosci.2652-11.2011","title":"Single-Channel and Structural Foundations of Neuronal α7 Acetylcholine Receptor Potentiation","year":2011,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Long-term potentiation; Acetylcholine; Agonist; Neuroscience; Acetylcholine receptor; Chemistry; Biophysics; Neurotransmission; Pharmacology; Receptor; Biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000203981,0.00009551187,0.0001340899,0.00007035423,0.00007139004,0.00001606692,0.0002316321,0.00004555734,0.00001008975],"category_scores_gemma":[0.0004085086,0.00008074509,0.00006967173,0.0001325793,0.0001815035,0.00002795061,0.0001090011,0.000111959,5.503101e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007560179,"about_ca_system_score_gemma":0.00006425811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003460845,"about_ca_topic_score_gemma":0.000002251655,"domain_scores_codex":[0.9990532,0.00005788758,0.0003612608,0.0001744272,0.0002156087,0.0001375845],"domain_scores_gemma":[0.9991024,0.00001195984,0.0004508838,0.0001348697,0.0002148468,0.00008503018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005251704,0.00007208146,0.002578143,0.000004407389,0.000005273387,2.904847e-7,0.00009629113,0.00002564021,0.9960757,0.00002096188,0.0001479813,0.0009206805],"study_design_scores_gemma":[0.001250081,0.002781987,0.109895,0.00002719039,0.00005151314,0.0004184769,0.0001346761,0.0004719773,0.8806354,0.0001643197,0.00392563,0.0002437858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963994,0.0000901052,0.002499861,0.000134643,0.0007098377,0.00006615547,0.000007627581,0.000002487837,0.00008988752],"genre_scores_gemma":[0.9978336,0.000120962,0.001655281,0.0001376126,0.0001549783,5.629367e-7,0.00000218239,0.000009224354,0.00008555972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1154404,"threshold_uncertainty_score":0.3292689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03858496605291872,"score_gpt":0.2754926496962568,"score_spread":0.236907683643338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}