{"id":"W2043910557","doi":"10.1097/01.hjh.0000383833.83556.56","title":"DIFFERENCES IN BIOAVAILABILITY OF NIFEDIPINE OSMOTIC PUSH-PULL SYSTEMS: PREDICTIVE RESULTS FROM IN-VITRO COMPARED TO IN-VIVO: PP.38.496","year":2010,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bayer (Canada)","funders":"","keywords":"Cmax; In vivo; Medicine; Bioavailability; Pharmacology; Chromatography; In vitro; Nifedipine; Bioequivalence; Internal medicine; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002404395,0.0002461932,0.0011088,0.000439734,0.00005168574,0.00002020737,0.0004003386,0.000431383,0.00007290885],"category_scores_gemma":[0.001006182,0.0001991977,0.0001260614,0.0004572839,0.0001810914,0.0002262729,0.000100615,0.001504893,0.00002300479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001224231,"about_ca_system_score_gemma":0.0001454543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002211779,"about_ca_topic_score_gemma":0.001136999,"domain_scores_codex":[0.9960451,0.0009638694,0.001866728,0.0003480363,0.000395935,0.0003803614],"domain_scores_gemma":[0.9970098,0.00131537,0.0007060741,0.000288877,0.0004130336,0.0002668669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.01563864,0.002312886,0.310113,0.0001536023,0.0001493903,0.0006431303,0.004237134,0.002431279,0.65911,0.00001151183,0.00456217,0.0006371954],"study_design_scores_gemma":[0.03042824,0.00193241,0.7114362,0.001918098,0.0003399244,0.0005338709,0.01025031,0.1115021,0.1203286,0.0003743116,0.009932935,0.001022963],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992812,0.0009348484,0.00001233641,0.0007556871,0.004348917,0.000511124,0.0002697466,0.00001200528,0.0003433755],"genre_scores_gemma":[0.9991436,0.0001279466,0.0001304583,0.0002019649,0.000321147,0.000006727699,0.00001038069,0.00001290432,0.00004489073],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5387815,"threshold_uncertainty_score":0.8123048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1213667977964463,"score_gpt":0.3508151538160383,"score_spread":0.229448356019592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}