{"id":"W2043910557","doi":"10.1097/01.hjh.0000383833.83556.56","title":"DIFFERENCES IN BIOAVAILABILITY OF NIFEDIPINE OSMOTIC PUSH-PULL SYSTEMS: PREDICTIVE RESULTS FROM IN-VITRO COMPARED TO IN-VIVO: PP.38.496","year":2010,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Bayer (Canada)","funders":"","keywords":"Cmax; In vivo; Medicine; Bioavailability; Pharmacology; Chromatography; In vitro; Nifedipine; Bioequivalence; Internal medicine; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00143414,0.0005737853,0.0004576916,0.0004510872,0.0001226508,0.0003715664,0.0002056297,0.000437135,0.001303442],"category_scores_gemma":[0.00201019,0.0002800152,0.0004494191,0.0003002549,0.0003806466,0.0004582884,0.0001832297,0.0006327001,0.0006101857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003526416,"about_ca_system_score_gemma":0.0001125729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005493912,"about_ca_topic_score_gemma":0.0004243612,"domain_scores_codex":[0.9993801,0.0002468126,0.00004313555,0.00008994225,0.0002100861,0.00002997697],"domain_scores_gemma":[0.9986306,0.0008382125,0.0002597508,0.00007897941,0.0001354134,0.00005708406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009159106,0.0006142395,0.008619727,0.0003753009,0.0001303482,0.0003557686,0.0001170332,0.0008301127,0.9245189,0.0001344436,0.000912982,0.05423208],"study_design_scores_gemma":[0.0001820694,0.02185789,0.09747486,0.00005575016,0.0004920809,0.002598387,0.0001331761,0.01371199,0.8557205,0.0003314852,0.007376841,0.00006499828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9651903,0.02126353,0.00931718,0.0004053278,0.0002389661,0.0001634825,0.000834036,0.0001469888,0.00244005],"genre_scores_gemma":[0.9829654,0.007817981,0.004813648,0.0001706961,0.0002244586,0.0001087767,0.0009703758,0.00007608512,0.002852467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00143414,"threshold_uncertainty_score":0.007584512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1213667977964463,"score_gpt":0.3508151538160383,"score_spread":0.229448356019592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}