{"id":"W2043935805","doi":"10.1016/j.molimm.2014.01.008","title":"Inducible costimulator facilitates T-dependent B cell activation by augmenting IL-4 translation","year":2014,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Germinal center; PI3K/AKT/mTOR pathway; Cell biology; T cell; Population; Signal transduction; Chemistry; Biology; B cell; Immune system; Immunology; Antibody; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002708038,0.000830834,0.000367385,0.0004582288,0.0002518057,0.0005844317,0.0003494441,0.0004566675,0.003063552],"category_scores_gemma":[0.0002589792,0.0002097601,0.0004482801,0.0002209727,0.0003155948,0.0003218174,0.0006016833,0.001431659,0.0007738807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000514893,"about_ca_system_score_gemma":0.0003544561,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002957078,"about_ca_topic_score_gemma":0.0004928274,"domain_scores_codex":[0.9996347,0.00008746534,0.00003368676,0.00004438551,0.00004861976,0.0001510873],"domain_scores_gemma":[0.9997332,0.00005353849,0.00006134222,0.00003937026,0.00002351941,0.00008902712],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000496933,0.00009223606,0.0001351157,0.00002922535,0.000004660273,0.00006173408,0.00000888361,0.00005943758,0.9977989,0.0001464863,0.00006162251,0.001104687],"study_design_scores_gemma":[0.00008222894,0.0003345193,0.001681224,0.000005556436,0.00001821241,0.00007804355,0.00001628466,0.0004689153,0.9960756,0.00004988926,0.001186023,0.000003523606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946622,0.001076292,0.001979426,0.0001859935,0.0001028489,0.00004252671,0.0001911069,0.0001588314,0.001600839],"genre_scores_gemma":[0.9928026,0.0004281338,0.003555688,0.00007984287,0.00008808233,0.00008376985,0.0005082302,0.00005818034,0.002395412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003063552,"threshold_uncertainty_score":0.0102486,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009458793153808093,"score_gpt":0.2105478945594785,"score_spread":0.2010891014056704,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}