{"id":"W2044025778","doi":"10.1038/nrm2466","title":"The promise of human induced pluripotent stem cells for research and therapy","year":2008,"lang":"en","type":"review","venue":"Nature Reviews Molecular Cell Biology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":419,"is_retracted":false,"has_abstract":false,"ca_institutions":"Juvenile Diabetes Research Foundation","funders":"","keywords":"Induced pluripotent stem cell; Reprogramming; Embryonic stem cell; Regenerative medicine; Somatic cell; Human Induced Pluripotent Stem Cells; Stem cell; Biology; Cell therapy; Cell potency; Cell biology; Cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002228435,0.001197008,0.001757476,0.001287632,0.0004088253,0.001403558,0.001512935,0.002876043,0.005058998],"category_scores_gemma":[0.001185289,0.0002988318,0.0005115896,0.001421312,0.001487209,0.003195466,0.001163385,0.00447949,0.00270492],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001079617,"about_ca_system_score_gemma":0.001206088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007263553,"about_ca_topic_score_gemma":0.001463648,"domain_scores_codex":[0.9996433,0.00008163356,0.00003316895,0.00004428927,0.000166586,0.00003097341],"domain_scores_gemma":[0.9992253,0.0004623914,0.00003678875,0.00003163997,0.0001642588,0.00007969039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001345616,0.00006500091,0.000131707,0.005268811,0.00007523021,0.000374864,0.00008096904,0.0006517497,0.006753011,0.03050455,0.1044019,0.8515576],"study_design_scores_gemma":[0.00003103489,0.00004310897,0.0001521097,0.0005561984,0.00003359367,0.0004385129,0.00003944306,0.00008592165,0.0007577699,0.009503067,0.9883471,0.00001215423],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001422281,0.9907323,0.001409346,0.003186997,0.002103029,0.000008846321,0.00003955092,0.00002758078,0.002350186],"genre_scores_gemma":[0.0008927863,0.9934106,0.001043872,0.0018279,0.001015499,0.00001341203,0.0000530884,0.00000479614,0.001737949],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005058998,"threshold_uncertainty_score":0.01692408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.109004600548994,"score_gpt":0.4171959208418612,"score_spread":0.3081913202928672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}