{"id":"W2044037627","doi":"10.2337/db06-0519","title":"Diabetes-Induced Extracellular Matrix Protein Expression Is Mediated by Transcription Coactivator p300","year":2006,"lang":"en","type":"article","venue":"Diabetes","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Diabetes Association","keywords":"Fibronectin; Coactivator; Small interfering RNA; Extracellular matrix; Poly ADP ribose polymerase; Biology; Cell biology; Transcription factor; Molecular biology; Chemistry; Internal medicine; Endocrinology; Cancer research; Medicine; Biochemistry; RNA; Polymerase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007270838,0.0003099904,0.0001192801,0.0001911495,0.0001111302,0.0001758658,0.000113892,0.0001127083,0.001072304],"category_scores_gemma":[0.0000999672,0.00008951547,0.000174873,0.0001222114,0.0001334717,0.00008850331,0.0001377992,0.0003227745,0.000346883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002659,"about_ca_system_score_gemma":0.0001068639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007892096,"about_ca_topic_score_gemma":0.0008487927,"domain_scores_codex":[0.9999254,0.000008886155,0.000004471675,0.00001714201,0.00002477945,0.00001920847],"domain_scores_gemma":[0.9999362,0.000009396571,0.000020815,0.000005846066,0.000009581244,0.0000181313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000629467,0.00001027138,0.0001553781,0.00001988526,0.000002531515,0.00006727914,0.000004183766,0.00001115069,0.9979684,0.00005412406,0.00006629806,0.001577595],"study_design_scores_gemma":[0.00004156147,0.0002265021,0.03410649,0.000008595544,0.00002028653,0.0008337566,0.00002761153,0.001156883,0.9583125,0.000202753,0.005054798,0.000008299098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766071,0.0075424,0.009664943,0.0003262013,0.00006761811,0.00002907622,0.0007501604,0.0002222392,0.00479021],"genre_scores_gemma":[0.9918617,0.002027891,0.002119514,0.00006558706,0.00001672608,0.00002136085,0.0006615914,0.0000164972,0.003209125],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001072304,"threshold_uncertainty_score":0.003587246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00721886854002687,"score_gpt":0.2121819678452339,"score_spread":0.204963099305207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}