{"id":"W2044183449","doi":"10.1021/bi700536p","title":"Mechanism of GlvA from <i>Bacillus subtilis</i>:  A Detailed Kinetic Analysis of a 6-Phospho-α-glucosidase from Glycoside Hydrolase Family 4","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health","keywords":"Chemistry; Enzyme kinetics; Stereochemistry; Hydrolase; Hydrolysis; Kinetic isotope effect; Glycoside hydrolase; Bacillus subtilis; Leaving group; Enzyme; Deuterium; Active site; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001475028,0.0005199218,0.00038867,0.0001424511,0.0001568869,0.000387516,0.0003374509,0.0003369479,0.0007379554],"category_scores_gemma":[0.0001882661,0.0002444634,0.0004245109,0.0001936344,0.0002171308,0.000437244,0.0002267014,0.0004811636,0.0004667428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000393322,"about_ca_system_score_gemma":0.0003061803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001386444,"about_ca_topic_score_gemma":0.000669472,"domain_scores_codex":[0.9998784,0.00001576469,0.000007239689,0.00002954355,0.00003697991,0.00003210481],"domain_scores_gemma":[0.9999262,0.00001400899,0.00001946336,0.000007424178,0.00001826347,0.00001472808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001873303,0.00002512911,0.0009210928,0.0001563429,0.00001734187,0.0001183127,0.00003404725,0.001243165,0.9925108,0.0003679646,0.0001067337,0.00431167],"study_design_scores_gemma":[0.000009326379,0.0001443694,0.002718946,0.000008524366,0.00001333728,0.0003471951,0.00003293484,0.003782788,0.9911954,0.0001372667,0.001591915,0.0000178845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797857,0.002151396,0.01319665,0.0001804559,0.00003719144,0.00006904975,0.0005507928,0.0001925482,0.003836304],"genre_scores_gemma":[0.9915665,0.001183449,0.004443903,0.00003662583,0.000005394161,0.0000341432,0.0007970161,0.00003289308,0.001900067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001386444,"threshold_uncertainty_score":0.002853751,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00631697530254702,"score_gpt":0.2197121727401683,"score_spread":0.2133951974376213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}