{"id":"W2044279929","doi":"10.1097/tp.0000000000000227","title":"Increased Osteoprotegerin Predicts Poor Virological Outcome During Anticytomegalovirus Therapy in Solid Organ Transplant Recipients","year":2014,"lang":"en","type":"article","venue":"Transplantation","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Osteoprotegerin; Medicine; Valganciclovir; Ganciclovir; Inflammation; Cytomegalovirus; Systemic inflammation; Internal medicine; Immunology; C-reactive protein; Transplantation; Gastroenterology; Human cytomegalovirus; Viral disease; Virus; Herpesviridae; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001925474,0.0001892401,0.0002122717,0.00008332717,0.00006523859,0.00002104529,0.0001418391,0.0001569263,0.00003017067],"category_scores_gemma":[0.00002511166,0.0001653556,0.00007454114,0.0001025934,0.00004878447,0.00001238237,0.000008025476,0.00009207735,0.000016784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007546852,"about_ca_system_score_gemma":0.00002285617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001007889,"about_ca_topic_score_gemma":0.00008768971,"domain_scores_codex":[0.9987272,0.0001558212,0.0003211166,0.0003555949,0.0001623982,0.0002778466],"domain_scores_gemma":[0.9995996,0.0000168025,0.00006035018,0.0001881657,0.00002426501,0.0001107739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002172862,0.000144224,0.2619758,0.00004907418,0.00001617405,0.00002224212,0.0001339081,0.00008158756,0.7343413,0.0000208446,0.000003286975,0.001038655],"study_design_scores_gemma":[0.003508099,0.0001969846,0.6911587,0.00002232254,0.00002364077,0.00002190939,0.000006908658,0.00005542992,0.3047395,0.00002529921,0.00007222551,0.0001690208],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979817,0.000144223,0.001091968,0.0000466308,0.000103127,0.0003081986,0.0001076867,0.00003511862,0.0001813882],"genre_scores_gemma":[0.9981188,0.0007868959,0.0001249472,0.0002534183,0.0001280276,0.00004373736,0.0004896251,0.00002222529,0.00003239314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4296018,"threshold_uncertainty_score":0.6743007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01180473367460652,"score_gpt":0.2529253260110552,"score_spread":0.2411205923364486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}