{"id":"W2044279929","doi":"10.1097/tp.0000000000000227","title":"Increased Osteoprotegerin Predicts Poor Virological Outcome During Anticytomegalovirus Therapy in Solid Organ Transplant Recipients","year":2014,"lang":"en","type":"article","venue":"Transplantation","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Osteoprotegerin; Medicine; Valganciclovir; Ganciclovir; Inflammation; Cytomegalovirus; Systemic inflammation; Internal medicine; Immunology; C-reactive protein; Transplantation; Gastroenterology; Human cytomegalovirus; Viral disease; Virus; Herpesviridae; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004072209,0.0002623443,0.0002837126,0.0003622895,0.0002113734,0.0004707607,0.000167098,0.0003151534,0.001306118],"category_scores_gemma":[0.0009378578,0.0001203743,0.0003014288,0.0003517173,0.0001920553,0.000200967,0.0002613605,0.000436304,0.0001510147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001679031,"about_ca_system_score_gemma":0.0001663015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005948138,"about_ca_topic_score_gemma":0.0008859496,"domain_scores_codex":[0.9998287,0.00004385257,0.00002241881,0.00003146169,0.00003189572,0.00004157909],"domain_scores_gemma":[0.9989946,0.0002044517,0.0004533396,0.00003525343,0.00005217121,0.0002600753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007854543,0.00003409182,0.9966253,0.000009510112,0.00003356027,0.00003384866,0.00001411461,0.00006454565,0.0009416561,0.000006994858,0.00004586432,0.001404988],"study_design_scores_gemma":[0.00002939515,0.0005274024,0.9982823,0.000005274771,0.00003507955,0.0002668206,0.00005085245,0.0003725555,0.0003109202,0.00002006917,0.0000967749,0.000002723734],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994622,0.0002461063,0.00004423453,0.00001531091,0.000003601185,0.000004190276,0.00006820095,0.000001760474,0.0001544287],"genre_scores_gemma":[0.999762,0.00003863814,0.00003106077,0.000008536754,0.000006155064,0.000002715264,0.00009874642,5.525401e-7,0.00005160684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001306118,"threshold_uncertainty_score":0.004369378,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01180473367460652,"score_gpt":0.2529253260110552,"score_spread":0.2411205923364486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}