{"id":"W2044366012","doi":"10.1021/bi001797+","title":"The Insulin-Stimulated Cell Surface Presentation of Low Density Lipoprotein Receptor-Related Protein in 3T3-L1 Adipocytes Is Sensitive to Phosphatidylinositide 3-Kinase Inhibition","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"GLUT4; Insulin; Insulin receptor; 3T3-L1; Endocrinology; Internal medicine; Chemistry; Endocytosis; Internalization; Cell; Low-density lipoprotein; Insulin receptor substrate; Receptor; Insulin resistance; Biology; Adipose tissue; Adipocyte; Cholesterol; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002307861,0.0002258338,0.0001826683,0.00002416067,0.0001054329,0.00002299065,0.0001186658,0.0003233904,0.00009718169],"category_scores_gemma":[0.00004251273,0.0002169832,0.0001072103,0.0002601991,0.0001074204,0.000008368004,0.00003250893,0.0001635356,0.00002845173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004622871,"about_ca_system_score_gemma":0.00009375064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002972073,"about_ca_topic_score_gemma":0.0000544492,"domain_scores_codex":[0.9985335,0.00007215341,0.0004437853,0.0004581292,0.0002177716,0.0002746805],"domain_scores_gemma":[0.9991986,0.00001667418,0.0001350144,0.0003679579,0.0001754263,0.0001062952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007538098,0.0001345006,0.0004979723,0.00007571883,0.00002467499,0.000009559084,0.0002137826,0.0004800263,0.9963369,0.000001861829,0.00009920844,0.001372029],"study_design_scores_gemma":[0.0009389729,0.0001232004,0.001764475,0.0001347578,0.00001493373,0.000003056548,0.0000979282,0.0004174867,0.995828,0.00001573287,0.0004131054,0.0002483355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978889,0.0004883091,0.0002397045,0.0001689538,0.00003552491,0.0007145978,0.0000669068,0.00001924125,0.0003778491],"genre_scores_gemma":[0.9956065,0.0001635176,0.0003648364,0.00006632677,0.00005337425,0.00002313362,0.002265,0.00002594201,0.001431413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002282456,"threshold_uncertainty_score":0.8848318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003608422324744109,"score_gpt":0.2008065233893254,"score_spread":0.1971981010645813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}