{"id":"W2044441423","doi":"10.1016/j.joca.2006.02.008","title":"Link protein can retard the degradation of hyaluronan in proteoglycan aggregates","year":2006,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Shriners Hospitals for Children - Canada","funders":"","keywords":"Aggrecan; Chemistry; Proteoglycan; Proteolysis; Hyaluronidase; Catabolism; Degradation (telecommunications); Cleavage (geology); Size-exclusion chromatography; Cartilage; Gel electrophoresis; Biochemistry; Biophysics; Extracellular matrix; Articular cartilage; Osteoarthritis; Anatomy; Metabolism; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003489389,0.0005304286,0.0002509692,0.0004609384,0.000269409,0.000423151,0.0002844504,0.000631851,0.001512259],"category_scores_gemma":[0.0004234244,0.0002286714,0.0003435077,0.0001808123,0.0003321664,0.0004204495,0.0003203871,0.0004433913,0.0006943247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003119251,"about_ca_system_score_gemma":0.0002307297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005521325,"about_ca_topic_score_gemma":0.0006718282,"domain_scores_codex":[0.9998523,0.00003328332,0.000009890138,0.00002093187,0.00003865792,0.00004499029],"domain_scores_gemma":[0.9997359,0.00006707083,0.00005675862,0.00002536474,0.00004108036,0.0000737673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005419544,0.00009464278,0.0002359167,0.0000861618,0.00002642828,0.0001246217,0.00002148176,0.00009717115,0.9966182,0.0002466531,0.0001516797,0.001755151],"study_design_scores_gemma":[0.00005128167,0.0003590856,0.002631044,0.0000101512,0.00003120403,0.000371939,0.0000155365,0.0007662754,0.9924455,0.0001541322,0.00315604,0.000007889839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893994,0.004730314,0.003376382,0.000199408,0.00007421821,0.00002563345,0.0001469457,0.00008708066,0.001960766],"genre_scores_gemma":[0.9877022,0.002148741,0.002499222,0.0002523022,0.00005610394,0.00003104559,0.0006908159,0.00007350247,0.00654613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001512259,"threshold_uncertainty_score":0.005059004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008383214660642414,"score_gpt":0.2219694762791946,"score_spread":0.2135862616185522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}