{"id":"W2044503653","doi":"10.1371/journal.pone.0003936","title":"Phosphorylation by Cdk1 Increases the Binding of Eg5 to Microtubules In Vitro and in Xenopus Egg Extract Spindles","year":2008,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Deutsche Forschungsgemeinschaft","keywords":"Xenopus; Cell biology; Microtubule; Kinesin; Biology; Spindle apparatus; Motor protein; Phosphorylation; Cyclin-dependent kinase 1; Mitosis; Spindle pole body; Biochemistry; Cell cycle; Cell division; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001126158,0.0001004272,0.0001537288,0.00006322036,0.00003917776,0.000007458988,0.000102828,0.00008894594,0.000005108721],"category_scores_gemma":[0.00007464848,0.00008780449,0.00002309604,0.0001027767,0.00005622005,0.00000450752,0.00006584876,0.00007336564,0.000002234247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001494082,"about_ca_system_score_gemma":0.00002643136,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003572207,"about_ca_topic_score_gemma":0.0001610592,"domain_scores_codex":[0.9993389,0.00003813336,0.0001969777,0.0001982523,0.00007408745,0.0001536317],"domain_scores_gemma":[0.9996952,0.00002085204,0.00005822245,0.0001634079,0.00002605938,0.00003627803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001347173,0.0004244236,0.02698838,0.00002203677,0.00002457857,0.000002038153,0.0001088465,0.000004309914,0.9717833,0.00000155182,0.0001035528,0.000402228],"study_design_scores_gemma":[0.0003398468,0.00007805435,0.01112578,0.00005512243,0.00001189156,0.000005028559,0.00006583193,0.00003717774,0.9879841,0.000006980554,0.00018611,0.0001040536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972633,0.00224047,0.00002639351,0.00009092967,0.000007388654,0.0002582711,0.0000491156,0.000003343871,0.00006081786],"genre_scores_gemma":[0.9973323,0.00141195,0.0008851365,0.0001181658,0.00002666544,0.00002421179,0.00009395382,0.00001296769,0.00009462664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01620079,"threshold_uncertainty_score":0.3580563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01589679510228327,"score_gpt":0.2161207494835291,"score_spread":0.2002239543812458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}