{"id":"W2044510808","doi":"10.1016/j.bpj.2013.11.1580","title":"Decoupling Conformation, Aggregation and Function of Amyloid-β Monomers and Oligomers: An Fcs, Sers and Afm Study","year":2014,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Monomer; Oligomer; Lipid bilayer; Peptide; Biophysics; Membrane; Amyloid beta; Amyloid (mycology); Biochemistry; Polymer; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002449821,0.0002677885,0.0001792594,0.0001952568,0.0004233246,0.0002224868,0.0003593348,0.0003290699,0.0009457055],"category_scores_gemma":[0.0002887476,0.0001581027,0.0002108284,0.0001799384,0.0004380713,0.0003545913,0.0002371611,0.0008057377,0.0002280696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002009202,"about_ca_system_score_gemma":0.0001586739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002071473,"about_ca_topic_score_gemma":0.00206694,"domain_scores_codex":[0.9998814,0.00001438021,0.000005362172,0.00002818178,0.00004464212,0.00002600457],"domain_scores_gemma":[0.9997584,0.0001133285,0.00002239984,0.00002835935,0.00005571162,0.0000217821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005489905,0.00002019758,0.0001645355,0.00001746682,0.000003538157,0.00003186137,0.00005951698,0.00006009257,0.9984069,0.0001443455,0.00003941354,0.0009971084],"study_design_scores_gemma":[0.0000120165,0.0001160676,0.00458364,0.000004910978,0.00001698948,0.0002404032,0.0001192011,0.003647626,0.9898474,0.0001916117,0.001207281,0.00001287638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930549,0.0008874299,0.003734381,0.0001473929,0.00002161788,0.00001409854,0.00007767572,0.00003104131,0.002031458],"genre_scores_gemma":[0.9941956,0.0005424855,0.003066065,0.00009147644,0.00002386074,0.00001468204,0.0001188812,0.00001360369,0.001933388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002071473,"threshold_uncertainty_score":0.00411886,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01958310030879495,"score_gpt":0.295733051803504,"score_spread":0.276149951494709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}