{"id":"W2044552822","doi":"10.1124/jpet.104.067769","title":"N-Butyryl Glucosamine Increases Matrix Gene Expression by Chondrocytes","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research","keywords":"Glucosamine; Chondrocyte; Chemistry; Type II collagen; Aggrecan; Galactosamine; Messenger RNA; Proteoglycan; Gene expression; Cartilage; Osteoarthritis; Biochemistry; Northern blot; Lactate dehydrogenase; Molecular biology; Extracellular matrix; Biology; Gene; Enzyme; In vitro; Anatomy; Medicine; Articular cartilage; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002298878,0.0007786248,0.0004625551,0.0003680517,0.0003211358,0.000572739,0.0002146042,0.0004172571,0.002001978],"category_scores_gemma":[0.0002310267,0.000321473,0.0005347453,0.0002268761,0.0005853184,0.0003609039,0.0003405006,0.0007926388,0.0006172897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004633885,"about_ca_system_score_gemma":0.0006738122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003627746,"about_ca_topic_score_gemma":0.00809167,"domain_scores_codex":[0.9996299,0.00006957274,0.00003721561,0.00004222127,0.00008185799,0.0001393025],"domain_scores_gemma":[0.9996839,0.00005982777,0.00006306658,0.0000433516,0.00003483758,0.0001151329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007039582,0.00003988563,0.0001073202,0.00002282903,0.000003106573,0.00005135728,0.00001824325,0.00001998094,0.9984976,0.00002929975,0.00002015871,0.0004863235],"study_design_scores_gemma":[0.00007676617,0.001527566,0.009417934,0.00001076256,0.00001710541,0.0001836482,0.0001685931,0.0002443878,0.9874012,0.00005666529,0.0008874206,0.000007998333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993848,0.002321135,0.001090832,0.0001767022,0.0001009254,0.0000288723,0.0002428109,0.00005251554,0.002138096],"genre_scores_gemma":[0.9897984,0.001253665,0.001262971,0.000134911,0.00004786233,0.00004370625,0.000484611,0.00003200004,0.006941781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003627746,"threshold_uncertainty_score":0.007213235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01586875807935855,"score_gpt":0.3317899862740514,"score_spread":0.3159212281946928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}