{"id":"W2044664896","doi":"10.1016/j.aquatox.2009.03.009","title":"Hepatic and vascular mRNA expression in adult zebrafish (Danio rerio) following exposure to benzo-a-pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin","year":2009,"lang":"en","type":"article","venue":"Aquatic Toxicology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Aryl hydrocarbon receptor; CYP1B1; Benzo(a)pyrene; Danio; Endocrinology; Internal medicine; Cytochrome P450; Gene expression; Chemistry; Resveratrol; Zebrafish; Biology; Pyrene; Pharmacology; Medicine; Biochemistry; Metabolism; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001096744,0.0002172339,0.0002195226,0.0003882073,0.000229732,0.000258798,0.0001371009,0.0002417769,0.001927791],"category_scores_gemma":[0.000139159,0.0003622292,0.0002901459,0.0001957757,0.0004113004,0.0002760934,0.0002001417,0.0004086019,0.0002470787],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005008476,"about_ca_system_score_gemma":0.0002631171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005003621,"about_ca_topic_score_gemma":0.010297,"domain_scores_codex":[0.9999126,0.000005724045,0.000004551931,0.00002930696,0.00001734687,0.00003035688],"domain_scores_gemma":[0.9998425,0.0000194871,0.00004377049,0.00000905419,0.00004246279,0.00004272479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004574529,0.00001331681,0.001571428,0.00003741173,0.000008717567,0.0001132869,0.00006617472,0.00002930898,0.9966639,0.0001108734,0.00004955015,0.0008787431],"study_design_scores_gemma":[0.0001034056,0.001268091,0.2878859,0.0000269784,0.0001726537,0.0006613296,0.0005688328,0.000778886,0.7054809,0.0002208686,0.002806164,0.00002595784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953672,0.0007013464,0.0009031587,0.00007866802,0.00002752518,0.00001661836,0.000727192,0.0000368152,0.002141579],"genre_scores_gemma":[0.9785255,0.0009646743,0.002076153,0.0001348567,0.00002432341,0.0001035808,0.001154324,0.00003596283,0.01698067],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005003621,"threshold_uncertainty_score":0.009949028,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006559523696314169,"score_gpt":0.2279769219565265,"score_spread":0.2214173982602124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}