{"id":"W2044669188","doi":"10.1016/j.immuni.2010.12.006","title":"CuRTAiling Interferon Regulatory Factor Signaling with the E3 Ligase RAUL","year":2010,"lang":"en","type":"letter","venue":"Immunity","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"IRF7; IRF3; Interferon regulatory factors; Biology; Ubiquitin ligase; Interferon; Transcription factor; Innate immune system; Acquired immune system; Pattern recognition receptor; Cell biology; Receptor; Genetics; Ubiquitin; Gene; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.0005360175,0.0007005581,0.0007239146,0.0002346864,0.0007965242,0.0001150302,0.001452836,0.002848736,0.002531742],"category_scores_gemma":[0.0001193678,0.0004361801,0.000323942,0.0001396341,0.0009965722,0.0001426798,0.000284318,0.01594591,0.001107201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009587889,"about_ca_system_score_gemma":0.0002429055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004923602,"about_ca_topic_score_gemma":0.00007498157,"domain_scores_codex":[0.9967,0.001358366,0.0005102445,0.000485553,0.0001120181,0.0008337561],"domain_scores_gemma":[0.9966291,0.0009624842,0.0004268102,0.001737335,0.0002215247,0.00002281482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009063452,0.00005780431,0.00001705143,0.00007143542,0.0006029666,0.00006401995,0.001236193,0.000001031074,0.5879475,0.0000154423,0.4069119,0.002168288],"study_design_scores_gemma":[0.0005279638,0.0003691877,0.0001280692,0.0002040974,0.0001009239,0.0002041012,0.0002829118,4.731958e-7,0.3550971,0.00001125652,0.642657,0.0004168377],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8979298,0.004977449,0.00008130269,0.09217957,0.002534592,0.0006105168,0.0001272552,0.0002576351,0.001301855],"genre_scores_gemma":[0.8152164,0.00007759948,0.00002595826,0.1505463,0.0007169765,0.00007074272,0.000723396,0.0001668294,0.03245576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2357451,"threshold_uncertainty_score":0.999809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01542277106734987,"score_gpt":0.2340103784570894,"score_spread":0.2185876073897396,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}