{"id":"W2044680993","doi":"10.1016/j.nbd.2014.10.005","title":"Laminar and cellular analyses of reduced somatostatin gene expression in the subgenual anterior cingulate cortex in major depression","year":2014,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":101,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; National Institutes of Health","keywords":"Somatostatin; Anterior cingulate cortex; Neuroscience; Internal medicine; Endocrinology; Major depressive disorder; Cingulate cortex; Psychology; Prefrontal cortex; In situ hybridization; Biology; Neuropeptide; Gene expression; Medicine; Gene; Central nervous system; Receptor; Genetics; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000138793,0.0001181438,0.0002241374,0.0001441255,0.00003673083,0.000005692604,0.0002266222,0.00004905893,0.00001190005],"category_scores_gemma":[0.0003341591,0.00008240247,0.00004638311,0.0001808077,0.0002672785,0.00005219407,0.000081752,0.00009272291,0.000001070036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002675045,"about_ca_system_score_gemma":0.00001921473,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001999003,"about_ca_topic_score_gemma":0.000009061383,"domain_scores_codex":[0.998464,0.000635092,0.0002979097,0.0003357419,0.0000896029,0.0001776927],"domain_scores_gemma":[0.9992221,0.0002983186,0.0001589858,0.0002580716,0.00001055137,0.00005199193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002905957,0.0001488297,0.02300558,0.00004444473,8.39738e-7,0.0000100971,0.000265637,0.00002217084,0.9758213,0.00001239282,0.00001524012,0.0003629415],"study_design_scores_gemma":[0.0006703554,0.00007971924,0.3402928,0.00004232805,0.00000558477,0.000001117967,0.00004841619,0.000124968,0.6585452,0.0001319071,0.000004511361,0.00005307733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994214,0.0001461566,0.00001947386,0.0001045269,0.00005074918,0.0001945806,0.00002425559,0.000009587934,0.00002923265],"genre_scores_gemma":[0.9995914,0.00004250148,0.00004947746,0.0002780754,0.000008456021,0.00000889896,0.000005824984,0.000008797746,0.00000663433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3172872,"threshold_uncertainty_score":0.3360275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01953545116105946,"score_gpt":0.2796299787141329,"score_spread":0.2600945275530734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}